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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C7orf57
All Species:
17.58
Human Site:
S140
Identified Species:
42.96
UniProt:
Q8NEG2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEG2
NP_001093629.1
295
32872
S140
N
P
D
Q
A
N
G
S
Y
A
S
R
R
G
P
Chimpanzee
Pan troglodytes
XP_001146768
459
50638
S304
N
P
D
Q
A
N
G
S
Y
A
S
R
R
G
P
Rhesus Macaque
Macaca mulatta
XP_001087879
335
37490
S185
N
P
D
Q
A
N
G
S
Y
A
S
R
R
G
P
Dog
Lupus familis
XP_537883
221
24309
F78
D
Y
M
V
Y
E
E
F
H
P
E
P
A
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SS90
291
32877
S140
N
P
D
Q
A
N
G
S
Y
E
S
R
Q
G
P
Rat
Rattus norvegicus
A0JPQ1
292
32739
S140
N
P
D
Q
A
N
G
S
Y
E
S
R
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506934
334
37914
I142
N
P
N
Q
A
N
G
I
Y
E
S
K
R
G
P
Chicken
Gallus gallus
XP_419025
256
29005
F113
D
Y
M
I
H
K
E
F
N
V
D
D
H
H
S
Frog
Xenopus laevis
NP_001090476
226
25709
D84
A
K
Q
G
G
R
P
D
L
L
K
Q
I
E
N
Zebra Danio
Brachydanio rerio
XP_690269
216
23374
D74
R
G
L
L
W
H
D
D
P
V
E
P
I
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
81.1
49.4
N.A.
73.5
71.5
N.A.
51.7
44.7
36.2
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.8
82.9
58.3
N.A.
83.7
81.3
N.A.
64
59.6
51.1
41
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
86.6
N.A.
73.3
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
86.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
60
0
0
0
0
30
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
50
0
0
0
10
20
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
20
0
0
30
20
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
10
0
60
0
0
0
0
0
0
60
10
% G
% His:
0
0
0
0
10
10
0
0
10
0
0
0
10
10
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
0
20
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
0
0
10
10
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
10
10
0
0
0
0
0
% L
% Met:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
10
0
0
60
0
0
10
0
0
0
0
10
20
% N
% Pro:
0
60
0
0
0
0
10
0
10
10
0
20
0
0
60
% P
% Gln:
0
0
10
60
0
0
0
0
0
0
0
10
20
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
50
40
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
60
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
10
0
0
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
10
0
0
0
60
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _