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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZSWIM2 All Species: 5.76
Human Site: S542 Identified Species: 25.33
UniProt: Q8NEG5 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NEG5 NP_872327.2 633 72721 S542 G K Y H T S L S R V T K G C K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104099 633 73059 S542 G K Y H T S Q S R M T K G C T
Dog Lupus familis XP_535994 679 76520 S586 E K H Y T G Q S Q K M A K D C
Cat Felis silvestris
Mouse Mus musculus Q9D9X6 631 71774 Q540 K D H I G Q S Q K T S R G Y E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512759 411 45728 A321 P N Q K G T K A G P R N S G M
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788425 825 90752 I720 G S T S G Q L I G S S K S P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.7 68.4 N.A. 67.6 N.A. N.A. 27.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 28.2
Protein Similarity: 100 N.A. 96.3 77.3 N.A. 80.8 N.A. N.A. 41.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 N.A. 80 20 N.A. 6.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 N.A. 86.6 40 N.A. 40 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 17 % C
% Asp: 0 17 0 0 0 0 0 0 0 0 0 0 0 17 0 % D
% Glu: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 0 0 50 17 0 0 34 0 0 0 50 17 0 % G
% His: 0 0 34 34 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 17 0 0 0 17 0 0 0 0 0 0 0 % I
% Lys: 17 50 0 17 0 0 17 0 17 17 0 50 17 0 17 % K
% Leu: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 17 17 0 0 0 17 % M
% Asn: 0 17 0 0 0 0 0 0 0 0 0 17 0 0 0 % N
% Pro: 17 0 0 0 0 0 0 0 0 17 0 0 0 17 0 % P
% Gln: 0 0 17 0 0 34 34 17 17 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 34 0 17 17 0 0 0 % R
% Ser: 0 17 0 17 0 34 17 50 0 17 34 0 34 0 17 % S
% Thr: 0 0 17 0 50 17 0 0 0 17 34 0 0 0 17 % T
% Val: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 34 17 0 0 0 0 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _