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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MNS1
All Species:
18.74
Human Site:
S489
Identified Species:
45.82
UniProt:
Q8NEH6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEH6
NP_060835.1
495
60571
S489
R
K
V
Y
Q
Q
R
S
E
I
C
E
E
K
_
Chimpanzee
Pan troglodytes
XP_510433
495
60568
S489
R
K
V
Y
Q
Q
R
S
E
I
C
E
E
K
_
Rhesus Macaque
Macaca mulatta
XP_001091177
495
60683
S489
R
K
V
Y
Q
Q
R
S
E
I
C
E
D
K
_
Dog
Lupus familis
XP_535489
582
69946
S576
R
K
A
Y
Q
K
R
S
E
I
C
G
E
K
_
Cat
Felis silvestris
Mouse
Mus musculus
Q61884
491
60217
R482
D
M
L
G
E
E
F
R
K
A
Y
Q
K
R
D
Rat
Rattus norvegicus
Q6AXQ8
498
61221
S489
R
K
A
Y
Q
K
K
S
E
V
C
E
E
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514115
560
67712
G551
R
E
M
Y
E
K
R
G
Q
T
A
P
E
E
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBA8
486
60428
A473
S
N
F
K
Q
R
Q
A
D
I
F
S
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795163
482
59509
Q472
K
R
N
Y
S
G
R
Q
R
N
I
H
S
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P0C6E7
568
66017
S558
V
P
N
H
A
L
R
S
A
I
Q
E
W
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.7
76.8
N.A.
76.7
76.9
N.A.
57.5
N.A.
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
45.6
Protein Similarity:
100
100
99.3
81.2
N.A.
89.4
90.3
N.A.
74.8
N.A.
N.A.
74.9
N.A.
N.A.
N.A.
N.A.
66.8
P-Site Identity:
100
100
92.8
78.5
N.A.
0
66.6
N.A.
26.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
85.7
N.A.
46.6
93.3
N.A.
66.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
10
0
0
10
10
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
0
20
0
10
% D
% Glu:
0
10
0
0
20
10
0
0
50
0
0
50
50
20
10
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
10
0
0
0
10
0
0
20
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
60
10
0
0
0
0
% I
% Lys:
10
50
0
10
0
30
10
0
10
0
0
0
10
50
10
% K
% Leu:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
0
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
20
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
60
30
10
10
10
0
10
10
0
0
10
% Q
% Arg:
60
10
0
0
0
10
70
10
10
0
0
0
0
10
0
% R
% Ser:
10
0
0
0
10
0
0
60
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
10
0
30
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
70
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% _