KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP18
All Species:
15.76
Human Site:
S16
Identified Species:
31.52
UniProt:
Q8NEJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ0
NP_689724.3
188
21066
S16
P
V
Q
F
R
Q
P
S
V
S
G
L
S
Q
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110413
188
21064
S16
P
V
Q
F
R
Q
P
S
V
S
G
L
S
Q
I
Dog
Lupus familis
XP_543483
188
20991
V16
P
V
Q
F
R
Q
P
V
V
S
G
L
S
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE01
188
21100
S16
P
V
Q
I
P
Q
P
S
I
R
G
L
S
Q
I
Rat
Rattus norvegicus
Q6AXW7
204
22736
S16
P
V
Q
F
P
Q
P
S
I
S
G
L
S
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521266
188
20903
S16
P
V
L
L
R
H
P
S
V
F
G
L
S
R
I
Chicken
Gallus gallus
Q9PW71
375
41034
D173
S
C
G
T
P
L
H
D
Q
G
G
P
V
E
I
Frog
Xenopus laevis
Q4KL92
209
23732
V18
P
N
A
Y
A
S
V
V
D
P
D
T
G
Y
C
Zebra Danio
Brachydanio rerio
Q29RA3
189
21985
L20
E
T
P
S
C
Y
E
L
Q
K
H
F
T
H
G
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
V18
N
P
Y
A
A
V
R
V
D
P
D
S
D
Y
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492580
272
30591
K35
P
D
K
I
K
Q
R
K
I
N
M
I
V
N
A
Sea Urchin
Strong. purpuratus
XP_791539
182
20339
N13
H
A
H
F
H
L
I
N
E
I
T
N
S
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
94.1
N.A.
82.4
77.9
N.A.
80.8
20.5
28.7
29.6
26.6
N.A.
N.A.
26.1
40.4
Protein Similarity:
100
N.A.
100
96.2
N.A.
90.4
84.3
N.A.
88.3
32.2
46.4
45.5
41.9
N.A.
N.A.
42.6
63.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
86.6
N.A.
66.6
13.3
6.6
0
6.6
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
93.3
N.A.
73.3
20
13.3
6.6
6.6
N.A.
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
17
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
0
0
0
0
0
9
17
0
17
0
9
0
0
% D
% Glu:
9
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
42
0
0
0
0
0
9
0
9
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
9
59
0
9
0
9
% G
% His:
9
0
9
0
9
9
9
0
0
0
9
0
0
9
0
% H
% Ile:
0
0
0
17
0
0
9
0
25
9
0
9
0
0
67
% I
% Lys:
0
0
9
0
9
0
0
9
0
9
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
17
0
9
0
0
0
50
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
9
0
9
0
9
0
9
0
% N
% Pro:
67
9
9
0
25
0
50
0
0
17
0
9
0
0
0
% P
% Gln:
0
0
42
0
0
50
0
0
17
0
0
0
0
42
0
% Q
% Arg:
0
0
0
0
34
0
17
0
0
9
0
0
0
9
0
% R
% Ser:
9
0
0
9
0
9
0
42
0
34
0
9
59
0
0
% S
% Thr:
0
9
0
9
0
0
0
0
0
0
9
9
9
0
0
% T
% Val:
0
50
0
0
0
9
9
25
34
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
9
0
0
0
0
0
0
0
17
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _