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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP18
All Species:
22.42
Human Site:
T134
Identified Species:
44.85
UniProt:
Q8NEJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ0
NP_689724.3
188
21066
T134
L
L
D
A
H
T
W
T
K
S
C
R
P
I
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110413
188
21064
T134
L
L
D
A
H
T
W
T
K
S
C
R
P
I
I
Dog
Lupus familis
XP_543483
188
20991
T134
L
L
D
A
H
T
W
T
K
S
C
R
P
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE01
188
21100
T134
L
V
D
A
H
T
W
T
K
S
C
R
P
I
I
Rat
Rattus norvegicus
Q6AXW7
204
22736
T134
L
L
D
A
H
A
W
T
K
S
R
R
P
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521266
188
20903
T134
L
L
D
A
H
A
W
T
K
S
C
R
P
I
V
Chicken
Gallus gallus
Q9PW71
375
41034
V291
L
E
K
A
F
E
F
V
K
Q
R
R
S
I
I
Frog
Xenopus laevis
Q4KL92
209
23732
V136
T
P
N
S
K
L
L
V
N
C
A
M
G
R
S
Zebra Danio
Brachydanio rerio
Q29RA3
189
21985
F138
R
S
R
S
A
T
L
F
L
A
F
L
M
L
Q
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
L136
L
S
Q
P
H
N
V
L
V
H
C
V
M
G
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492580
272
30591
S153
K
R
L
R
G
T
A
S
V
K
M
V
Q
T
P
Sea Urchin
Strong. purpuratus
XP_791539
182
20339
R131
A
H
V
H
V
K
S
R
R
P
V
I
R
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
94.1
N.A.
82.4
77.9
N.A.
80.8
20.5
28.7
29.6
26.6
N.A.
N.A.
26.1
40.4
Protein Similarity:
100
N.A.
100
96.2
N.A.
90.4
84.3
N.A.
88.3
32.2
46.4
45.5
41.9
N.A.
N.A.
42.6
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
86.6
40
0
6.6
20
N.A.
N.A.
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
86.6
N.A.
93.3
46.6
13.3
26.6
20
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
59
9
17
9
0
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
50
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
9
9
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
9
9
0
% G
% His:
0
9
0
9
59
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
59
50
% I
% Lys:
9
0
9
0
9
9
0
0
59
9
0
0
0
0
0
% K
% Leu:
67
42
9
0
0
9
17
9
9
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
17
0
0
% M
% Asn:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
9
% N
% Pro:
0
9
0
9
0
0
0
0
0
9
0
0
50
9
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
9
0
0
9
0
9
% Q
% Arg:
9
9
9
9
0
0
0
9
9
0
17
59
9
9
9
% R
% Ser:
0
17
0
17
0
0
9
9
0
50
0
0
9
0
9
% S
% Thr:
9
0
0
0
0
50
0
50
0
0
0
0
0
9
0
% T
% Val:
0
9
9
0
9
0
9
17
17
0
9
17
0
0
9
% V
% Trp:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _