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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP18
All Species:
20.91
Human Site:
T163
Identified Species:
41.82
UniProt:
Q8NEJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ0
NP_689724.3
188
21066
T163
F
Q
L
F
G
K
N
T
V
H
M
V
S
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110413
188
21064
T163
F
Q
L
F
G
K
N
T
V
H
M
V
S
S
P
Dog
Lupus familis
XP_543483
188
20991
T163
F
Q
L
F
G
K
N
T
V
H
M
V
S
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE01
188
21100
T163
L
Q
L
F
G
K
N
T
M
Q
M
M
D
S
P
Rat
Rattus norvegicus
Q6AXW7
204
22736
T163
F
Q
L
F
G
K
N
T
M
Q
M
V
N
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521266
188
20903
S163
F
K
L
F
G
K
N
S
V
R
M
V
G
S
P
Chicken
Gallus gallus
Q9PW71
375
41034
C320
S
Q
V
L
A
T
S
C
A
V
E
A
A
S
P
Frog
Xenopus laevis
Q4KL92
209
23732
I165
N
M
T
V
V
E
S
I
T
Q
V
L
K
H
R
Zebra Danio
Brachydanio rerio
Q29RA3
189
21985
W167
R
R
H
I
C
P
N
W
G
F
L
K
Q
L
R
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
A165
H
S
L
S
V
V
D
A
I
E
H
V
R
Q
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492580
272
30591
E182
R
R
M
Q
I
N
R
E
I
S
R
H
S
L
P
Sea Urchin
Strong. purpuratus
XP_791539
182
20339
M160
Y
G
K
N
S
V
K
M
M
Y
T
H
A
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
94.1
N.A.
82.4
77.9
N.A.
80.8
20.5
28.7
29.6
26.6
N.A.
N.A.
26.1
40.4
Protein Similarity:
100
N.A.
100
96.2
N.A.
90.4
84.3
N.A.
88.3
32.2
46.4
45.5
41.9
N.A.
N.A.
42.6
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
66.6
80
N.A.
73.3
20
0
6.6
13.3
N.A.
N.A.
13.3
0
P-Site Similarity:
100
N.A.
100
100
N.A.
80
93.3
N.A.
86.6
40
26.6
20
26.6
N.A.
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
9
9
0
0
9
17
0
9
% A
% Cys:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
9
0
9
0
9
9
0
0
0
0
% E
% Phe:
42
0
0
50
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
0
50
0
0
0
9
0
0
0
9
9
0
% G
% His:
9
0
9
0
0
0
0
0
0
25
9
17
0
9
0
% H
% Ile:
0
0
0
9
9
0
0
9
17
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
50
9
0
0
0
0
9
9
0
0
% K
% Leu:
9
0
59
9
0
0
0
0
0
0
9
9
0
17
0
% L
% Met:
0
9
9
0
0
0
0
9
25
0
50
9
0
0
0
% M
% Asn:
9
0
0
9
0
9
59
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
67
% P
% Gln:
0
50
0
9
0
0
0
0
0
25
0
0
9
9
0
% Q
% Arg:
17
17
0
0
0
0
9
0
0
9
9
0
9
0
25
% R
% Ser:
9
9
0
9
9
0
17
9
0
9
0
0
34
59
0
% S
% Thr:
0
0
9
0
0
9
0
42
9
0
9
0
0
0
0
% T
% Val:
0
0
9
9
17
17
0
0
34
9
9
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _