KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGDN
All Species:
40
Human Site:
S139
Identified Species:
80
UniProt:
Q8NEJ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ9
NP_001036100.1
315
35894
S139
P
H
P
S
N
M
M
S
K
L
S
S
E
D
E
Chimpanzee
Pan troglodytes
XP_001163084
315
35789
S139
P
H
P
S
N
M
M
S
K
L
S
S
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001108182
311
35188
S139
P
H
P
S
N
M
M
S
K
L
S
S
E
D
E
Dog
Lupus familis
XP_547734
318
36281
S142
P
H
P
S
N
M
M
S
K
L
S
S
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB96
315
35640
S139
P
H
P
S
N
M
V
S
K
L
S
S
E
D
E
Rat
Rattus norvegicus
NP_001100733
315
35795
S139
P
H
P
S
N
M
M
S
K
L
S
S
E
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505953
316
35836
S139
P
H
P
S
N
L
I
S
K
L
S
S
S
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLC4
317
36090
S140
P
N
P
Q
N
L
M
S
K
L
S
E
P
D
E
Zebra Danio
Brachydanio rerio
Q6PFJ1
315
36183
S143
P
N
P
Q
S
L
V
S
K
L
S
E
S
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608956
332
37306
S144
P
N
P
D
D
M
M
S
S
A
G
G
A
G
R
Honey Bee
Apis mellifera
XP_625107
303
34687
S141
A
N
P
D
A
F
D
S
N
D
E
E
S
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190632
421
47439
S244
P
N
P
D
G
L
V
S
K
L
Q
D
E
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
91.8
N.A.
88.5
89.8
N.A.
81.6
N.A.
62.1
56.8
N.A.
41.5
41.9
N.A.
37
Protein Similarity:
100
99.3
97.1
94.9
N.A.
94.9
95.5
N.A.
91.1
N.A.
78.8
76.1
N.A.
62.3
62.8
N.A.
50.5
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
66.6
N.A.
66.6
40
N.A.
33.3
20
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
N.A.
80
80
N.A.
46.6
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
0
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
25
9
0
9
0
0
9
0
9
0
67
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
25
59
17
59
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
9
9
0
9
17
% G
% His:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
34
0
0
0
84
0
0
0
0
0
% L
% Met:
0
0
0
0
0
59
59
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
0
0
67
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
92
0
100
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
9
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
59
9
0
0
100
9
0
75
59
25
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _