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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGDN
All Species:
26.06
Human Site:
S143
Identified Species:
52.12
UniProt:
Q8NEJ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ9
NP_001036100.1
315
35894
S143
N
M
M
S
K
L
S
S
E
D
E
E
E
D
E
Chimpanzee
Pan troglodytes
XP_001163084
315
35789
S143
N
M
M
S
K
L
S
S
E
D
E
E
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001108182
311
35188
S143
N
M
M
S
K
L
S
S
E
D
E
E
E
D
E
Dog
Lupus familis
XP_547734
318
36281
S146
N
M
M
S
K
L
S
S
E
D
E
E
E
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB96
315
35640
S143
N
M
V
S
K
L
S
S
E
D
E
E
E
S
E
Rat
Rattus norvegicus
NP_001100733
315
35795
S143
N
M
M
S
K
L
S
S
E
D
E
E
E
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505953
316
35836
S143
N
L
I
S
K
L
S
S
S
E
G
E
E
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLC4
317
36090
E144
N
L
M
S
K
L
S
E
P
D
E
R
E
S
D
Zebra Danio
Brachydanio rerio
Q6PFJ1
315
36183
E147
S
L
V
S
K
L
S
E
S
E
D
S
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608956
332
37306
G148
D
M
M
S
S
A
G
G
A
G
R
D
E
D
D
Honey Bee
Apis mellifera
XP_625107
303
34687
E145
A
F
D
S
N
D
E
E
S
D
S
D
Q
D
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190632
421
47439
D248
G
L
V
S
K
L
Q
D
E
Q
G
E
E
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
91.8
N.A.
88.5
89.8
N.A.
81.6
N.A.
62.1
56.8
N.A.
41.5
41.9
N.A.
37
Protein Similarity:
100
99.3
97.1
94.9
N.A.
94.9
95.5
N.A.
91.1
N.A.
78.8
76.1
N.A.
62.3
62.8
N.A.
50.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
53.3
N.A.
60
33.3
N.A.
33.3
20
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
80
N.A.
73.3
80
N.A.
53.3
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
0
9
0
67
9
17
9
59
25
% D
% Glu:
0
0
0
0
0
0
9
25
59
17
59
67
84
9
42
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
9
9
0
9
17
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
34
0
0
0
84
0
0
0
0
0
0
0
0
0
% L
% Met:
0
59
59
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
0
9
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
0
0
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% R
% Ser:
9
0
0
100
9
0
75
59
25
0
9
9
0
17
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _