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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NGDN All Species: 16.06
Human Site: S168 Identified Species: 32.12
UniProt: Q8NEJ9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NEJ9 NP_001036100.1 315 35894 S168 K K S V K G V S K K Y V P P R
Chimpanzee Pan troglodytes XP_001163084 315 35789 S168 Q K S V K G V S K K Y V P P R
Rhesus Macaque Macaca mulatta XP_001108182 311 35188 S168 K K S V K G V S K K Y V P P R
Dog Lupus familis XP_547734 318 36281 I171 K K S A K G T I K K Y V P P R
Cat Felis silvestris
Mouse Mus musculus Q9DB96 315 35640 A168 K K S A K G S A K K Y V P P R
Rat Rattus norvegicus NP_001100733 315 35795 S168 K K S V K G A S K K Y V P P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505953 316 35836 S168 K K T Q K R G S S R K Y I P P
Chicken Gallus gallus
Frog Xenopus laevis Q4KLC4 317 36090 V169 A K K P Q S K V K R Y I P P R
Zebra Danio Brachydanio rerio Q6PFJ1 315 36183 Y172 E P S G G R R Y V P P R I A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608956 332 37306 D173 D D D E E D E D E A G A A K M
Honey Bee Apis mellifera XP_625107 303 34687 P170 K S N I Y V P P K L A A V H Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190632 421 47439 K273 P K K Y V P P K V A A M F Y D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.9 91.8 N.A. 88.5 89.8 N.A. 81.6 N.A. 62.1 56.8 N.A. 41.5 41.9 N.A. 37
Protein Similarity: 100 99.3 97.1 94.9 N.A. 94.9 95.5 N.A. 91.1 N.A. 78.8 76.1 N.A. 62.3 62.8 N.A. 50.5
P-Site Identity: 100 93.3 100 80 N.A. 80 93.3 N.A. 33.3 N.A. 40 6.6 N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 80 N.A. 86.6 93.3 N.A. 46.6 N.A. 60 13.3 N.A. 13.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 17 0 0 9 9 0 17 17 17 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 0 0 9 0 9 0 0 0 0 0 0 9 % D
% Glu: 9 0 0 9 9 0 9 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 9 9 50 9 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 9 0 0 0 9 0 0 0 9 17 0 0 % I
% Lys: 59 75 17 0 59 0 9 9 67 50 9 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 0 9 0 9 17 9 0 9 9 0 59 67 17 % P
% Gln: 9 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 17 9 0 0 17 0 9 0 0 59 % R
% Ser: 0 9 59 0 0 9 9 42 9 0 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 34 9 9 25 9 17 0 0 50 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 9 0 0 59 9 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _