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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGDN
All Species:
34.55
Human Site:
S252
Identified Species:
69.09
UniProt:
Q8NEJ9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ9
NP_001036100.1
315
35894
S252
M
M
V
R
L
S
V
S
K
R
E
K
G
R
R
Chimpanzee
Pan troglodytes
XP_001163084
315
35789
S252
M
M
V
R
L
S
V
S
K
R
E
K
G
R
R
Rhesus Macaque
Macaca mulatta
XP_001108182
311
35188
S252
M
M
V
R
L
S
I
S
K
R
E
K
G
R
R
Dog
Lupus familis
XP_547734
318
36281
S255
M
M
V
R
L
S
V
S
K
R
E
K
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB96
315
35640
S252
M
M
V
R
L
S
V
S
K
R
E
K
G
L
R
Rat
Rattus norvegicus
NP_001100733
315
35795
S252
M
M
V
R
L
S
V
S
K
R
E
K
G
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505953
316
35836
S253
M
M
V
R
L
S
V
S
K
R
E
R
G
R
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLC4
317
36090
T253
M
M
V
R
L
N
M
T
R
K
E
K
A
R
K
Zebra Danio
Brachydanio rerio
Q6PFJ1
315
36183
T255
M
M
V
R
L
S
T
T
R
D
Q
K
L
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608956
332
37306
K276
L
M
R
L
P
V
T
K
A
E
K
H
R
Q
R
Honey Bee
Apis mellifera
XP_625107
303
34687
Q252
T
R
L
P
V
T
K
Q
E
K
H
R
R
H
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190632
421
47439
K354
L
R
L
P
V
T
K
K
D
K
Q
R
E
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
91.8
N.A.
88.5
89.8
N.A.
81.6
N.A.
62.1
56.8
N.A.
41.5
41.9
N.A.
37
Protein Similarity:
100
99.3
97.1
94.9
N.A.
94.9
95.5
N.A.
91.1
N.A.
78.8
76.1
N.A.
62.3
62.8
N.A.
50.5
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
53.3
53.3
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
93.3
80
N.A.
33.3
46.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
67
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
59
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
17
59
25
9
67
0
0
17
% K
% Leu:
17
0
17
9
75
0
0
0
0
0
0
0
9
17
0
% L
% Met:
75
84
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
17
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
17
0
0
9
9
% Q
% Arg:
0
17
9
75
0
0
0
0
17
59
0
25
17
67
67
% R
% Ser:
0
0
0
0
0
67
0
59
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
17
17
17
0
0
0
0
0
0
0
% T
% Val:
0
0
75
0
17
9
50
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _