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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGDN
All Species:
27.27
Human Site:
S271
Identified Species:
54.55
UniProt:
Q8NEJ9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEJ9
NP_001036100.1
315
35894
S271
V
M
S
S
Q
L
H
S
L
T
H
F
S
D
I
Chimpanzee
Pan troglodytes
XP_001163084
315
35789
S271
V
M
S
S
Q
L
H
S
L
T
H
F
S
D
I
Rhesus Macaque
Macaca mulatta
XP_001108182
311
35188
S271
V
M
S
S
Q
L
H
S
L
T
H
F
S
D
I
Dog
Lupus familis
XP_547734
318
36281
S274
V
M
S
S
Q
L
H
S
L
T
H
F
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB96
315
35640
S271
A
M
S
S
Q
L
H
S
L
T
H
F
S
D
I
Rat
Rattus norvegicus
NP_001100733
315
35795
S271
A
M
S
S
Q
L
H
S
L
T
H
F
S
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505953
316
35836
N272
A
M
S
S
Q
L
H
N
L
T
H
F
S
D
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLC4
317
36090
S272
S
M
T
S
Q
L
N
S
L
T
H
F
S
D
I
Zebra Danio
Brachydanio rerio
Q6PFJ1
315
36183
N274
G
M
T
S
Q
L
S
N
I
T
R
F
S
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608956
332
37306
I295
L
G
T
L
G
D
E
I
L
G
E
I
S
R
E
Honey Bee
Apis mellifera
XP_625107
303
34687
T271
G
T
L
G
E
E
I
T
T
F
G
E
S
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190632
421
47439
R373
A
S
L
D
G
L
T
R
F
D
N
I
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
91.8
N.A.
88.5
89.8
N.A.
81.6
N.A.
62.1
56.8
N.A.
41.5
41.9
N.A.
37
Protein Similarity:
100
99.3
97.1
94.9
N.A.
94.9
95.5
N.A.
91.1
N.A.
78.8
76.1
N.A.
62.3
62.8
N.A.
50.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
80
60
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
93.3
80
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
9
0
0
0
9
0
0
0
75
0
% D
% Glu:
0
0
0
0
9
9
9
0
0
0
9
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
9
0
75
0
0
0
% F
% Gly:
17
9
0
9
17
0
0
0
0
9
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
59
0
0
0
67
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
9
0
0
17
0
0
75
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
17
9
0
84
0
0
75
0
0
0
0
0
9
% L
% Met:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
17
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
9
0
0
9
0
% R
% Ser:
9
9
59
75
0
0
9
59
0
0
0
0
100
9
9
% S
% Thr:
0
9
25
0
0
0
9
9
9
75
0
0
0
0
0
% T
% Val:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _