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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM46D
All Species:
15.45
Human Site:
Y283
Identified Species:
42.5
UniProt:
Q8NEK8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEK8
NP_689843.1
389
44500
Y283
Q
Q
K
K
I
E
S
Y
L
H
N
H
F
I
G
Chimpanzee
Pan troglodytes
XP_001144356
389
44344
Y283
Q
Q
K
K
I
E
S
Y
L
H
N
H
F
I
G
Rhesus Macaque
Macaca mulatta
XP_001102987
389
44388
Y283
Q
Q
K
K
I
E
S
Y
L
H
N
H
F
I
G
Dog
Lupus familis
XP_549103
390
44783
Y283
Q
Q
M
K
I
E
S
Y
L
R
N
H
F
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSF7
391
44778
F275
R
Y
M
C
S
R
F
F
I
D
F
P
D
I
L
Rat
Rattus norvegicus
Q5XIV0
391
44780
F275
R
Y
M
C
S
R
F
F
I
D
F
P
D
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL95
390
44734
F274
R
Y
M
C
S
R
F
F
I
D
F
P
D
I
L
Frog
Xenopus laevis
NP_001121299
402
45817
L296
I
G
E
Q
Q
R
K
L
E
S
Y
L
Q
N
H
Zebra Danio
Brachydanio rerio
Q7ZUP1
388
44738
Y270
E
F
K
A
L
E
R
Y
M
C
S
R
F
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
94
82
N.A.
58.3
58.8
N.A.
N.A.
56.1
58.7
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
96.4
88.7
N.A.
73.1
73.4
N.A.
N.A.
70.7
72.3
72.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
26.6
26.6
N.A.
N.A.
26.6
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
34
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
34
0
0
34
0
0
% D
% Glu:
12
0
12
0
0
56
0
0
12
0
0
0
0
0
0
% E
% Phe:
0
12
0
0
0
0
34
34
0
0
34
0
56
12
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
45
% G
% His:
0
0
0
0
0
0
0
0
0
34
0
45
0
0
12
% H
% Ile:
12
0
0
0
45
0
0
0
34
0
0
0
0
78
12
% I
% Lys:
0
0
45
45
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
12
45
0
0
12
0
0
34
% L
% Met:
0
0
45
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
45
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% P
% Gln:
45
45
0
12
12
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
34
0
0
0
0
45
12
0
0
12
0
12
0
0
0
% R
% Ser:
0
0
0
0
34
0
45
0
0
12
12
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
0
0
0
0
56
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _