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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCPH1
All Species:
8.18
Human Site:
T500
Identified Species:
30
UniProt:
Q8NEM0
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEM0
NP_078872.2
835
92772
T500
R
A
T
S
S
C
V
T
S
A
P
E
E
A
L
Chimpanzee
Pan troglodytes
P61593
835
92565
T500
R
A
T
S
S
C
V
T
S
A
P
E
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001097449
842
93458
T500
C
A
T
F
S
C
V
T
S
E
E
S
S
A
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT79
822
90355
E494
S
T
C
L
L
L
V
E
T
S
A
N
D
S
P
Rat
Rattus norvegicus
XP_225006
864
95404
T513
T
C
L
P
L
L
G
T
S
A
D
D
S
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001098789
513
58196
A196
T
A
S
Q
M
F
Q
A
S
P
R
C
S
Q
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035453
422
47765
V105
D
K
M
M
E
G
L
V
P
S
S
P
I
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
91
N.A.
N.A.
56.6
52.4
N.A.
N.A.
37.8
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
93.3
N.A.
N.A.
68.7
64.9
N.A.
N.A.
48.5
N.A.
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
N.A.
N.A.
6.6
20
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
N.A.
N.A.
33.3
26.6
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
0
0
0
15
0
43
15
0
0
43
0
% A
% Cys:
15
15
15
0
0
43
0
0
0
0
0
15
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
0
15
15
15
0
0
% D
% Glu:
0
0
0
0
15
0
0
15
0
15
15
29
29
0
0
% E
% Phe:
0
0
0
15
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
15
0
0
0
0
0
0
0
29
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
15
29
29
15
0
0
0
0
0
0
0
29
% L
% Met:
0
0
15
15
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% N
% Pro:
0
0
0
15
0
0
0
0
15
15
29
15
0
15
29
% P
% Gln:
0
0
0
15
0
0
15
0
0
0
0
0
0
15
0
% Q
% Arg:
29
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% R
% Ser:
15
0
15
29
43
0
0
0
72
29
15
15
43
15
15
% S
% Thr:
29
15
43
0
0
0
0
58
15
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
58
15
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _