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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
27.88
Human Site:
S1074
Identified Species:
51.11
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
S1074
T
R
K
K
S
L
L
S
A
A
L
A
K
S
G
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
S1074
T
R
K
K
S
L
L
S
A
A
L
A
K
S
G
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
A770
R
K
K
S
L
L
S
A
A
L
A
K
S
G
E
Dog
Lupus familis
XP_544039
1169
129817
S1089
S
R
K
K
S
L
L
S
A
A
L
S
K
S
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
S1067
T
R
K
K
S
V
L
S
A
A
L
A
K
S
G
Rat
Rattus norvegicus
NP_001100916
1152
128233
S1072
T
R
K
K
S
V
L
S
A
S
L
A
K
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
L827
K
S
L
L
S
S
A
L
A
K
S
G
E
R
L
Chicken
Gallus gallus
XP_426541
1160
128454
S1077
A
R
K
K
A
L
I
S
A
A
L
A
K
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
T1033
S
R
R
K
T
L
I
T
A
A
L
A
K
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
L958
L
A
K
S
T
S
K
L
L
Y
A
A
L
P
P
Honey Bee
Apis mellifera
XP_623825
843
94051
L764
G
K
F
L
Y
K
N
L
E
P
Q
E
R
V
E
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
S1199
M
Q
N
G
G
E
S
S
A
K
F
Q
G
L
D
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
D905
M
G
R
E
L
F
I
D
S
P
V
D
E
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
20
86.6
N.A.
93.3
86.6
N.A.
13.3
80
N.A.
66.6
N.A.
13.3
0
13.3
0
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
20
93.3
N.A.
100
N.A.
20
13.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
8
8
77
47
16
54
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
8
0
8
0
0
8
0
0
8
16
0
16
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
0
8
8
0
0
0
0
0
0
8
8
8
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% I
% Lys:
8
16
62
54
0
8
8
0
0
16
0
8
54
0
8
% K
% Leu:
8
0
8
16
16
47
39
24
8
8
54
0
8
8
8
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
8
54
16
0
0
0
0
0
0
0
0
0
8
16
0
% R
% Ser:
16
8
0
16
47
16
16
54
8
8
8
8
8
54
0
% S
% Thr:
31
0
0
0
16
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
16
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _