KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
24.55
Human Site:
S1108
Identified Species:
45
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
S1108
I
E
T
L
E
S
L
S
L
D
Q
H
S
K
K
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
S1108
I
E
T
L
E
S
L
S
L
D
Q
H
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
L804
E
T
L
E
S
L
S
L
D
Q
H
S
K
K
I
Dog
Lupus familis
XP_544039
1169
129817
S1123
L
E
S
L
E
S
L
S
L
D
Q
H
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
S1101
I
E
T
L
E
N
L
S
L
D
Q
H
S
K
K
Rat
Rattus norvegicus
NP_001100916
1152
128233
S1106
I
E
T
L
E
N
L
S
L
D
Q
H
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
Q861
L
E
N
A
P
V
D
Q
H
S
R
K
T
S
K
Chicken
Gallus gallus
XP_426541
1160
128454
S1111
I
E
S
L
E
S
M
S
S
D
R
Q
S
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
S1067
L
E
S
V
E
S
T
S
P
S
E
Q
H
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
L992
A
E
T
E
G
Y
T
L
M
N
D
A
E
K
A
Honey Bee
Apis mellifera
XP_623825
843
94051
G798
R
L
E
L
S
Q
S
G
E
M
D
S
I
K
L
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
P1233
C
Q
S
G
R
S
T
P
A
P
P
P
D
D
D
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
E939
R
Q
L
R
L
A
K
E
V
Q
L
S
R
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
93.3
N.A.
13.3
60
N.A.
26.6
N.A.
20
13.3
6.6
0
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
33.3
86.6
N.A.
53.3
N.A.
33.3
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
0
0
8
0
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
47
16
0
8
8
8
% D
% Glu:
8
70
8
16
54
0
0
8
8
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
8
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
39
8
0
0
% H
% Ile:
39
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
8
8
70
47
% K
% Leu:
24
8
16
54
8
8
39
16
39
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
16
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
8
8
8
8
0
0
0
% P
% Gln:
0
16
0
0
0
8
0
8
0
16
39
16
0
0
0
% Q
% Arg:
16
0
0
8
8
0
0
0
0
0
16
0
8
8
16
% R
% Ser:
0
0
31
0
16
47
16
54
8
16
0
24
47
8
0
% S
% Thr:
0
8
39
0
0
0
24
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _