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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
17.27
Human Site:
S452
Identified Species:
31.67
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
S452
Y
E
R
P
V
G
Q
S
N
Q
G
A
V
L
Q
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
S452
Y
E
R
P
V
G
Q
S
N
Q
G
A
V
L
Q
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
N204
A
S
D
V
R
A
Q
N
E
F
K
D
E
A
Q
Dog
Lupus familis
XP_544039
1169
129817
S467
Y
E
R
P
V
G
Q
S
N
Q
G
A
A
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
Q450
Y
Y
Q
R
P
A
G
Q
S
S
Q
D
S
L
G
Rat
Rattus norvegicus
NP_001100916
1152
128233
S451
Y
Q
R
P
V
G
Q
S
N
Q
G
A
M
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
T261
S
P
K
R
T
V
S
T
F
A
A
K
P
L
G
Chicken
Gallus gallus
XP_426541
1160
128454
N460
Y
E
R
P
V
G
Y
N
Q
H
G
S
A
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
T444
E
E
D
P
A
P
I
T
T
M
D
I
S
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
L392
N
L
L
A
G
D
V
L
V
A
I
E
G
R
P
Honey Bee
Apis mellifera
XP_623825
843
94051
R198
R
Y
K
P
F
F
R
R
L
N
D
E
A
V
A
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
S471
F
D
K
P
P
S
V
S
V
Q
R
A
E
S
A
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
V339
T
D
L
R
K
G
D
V
V
L
D
I
D
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
13.3
93.3
N.A.
13.3
86.6
N.A.
6.6
60
N.A.
13.3
N.A.
0
6.6
26.6
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
26.6
100
N.A.
20
73.3
N.A.
20
N.A.
0
26.6
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
16
0
0
0
16
8
39
24
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
16
0
0
8
8
0
0
0
24
16
8
0
0
% D
% Glu:
8
39
0
0
0
0
0
0
8
0
0
16
16
8
0
% E
% Phe:
8
0
0
0
8
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
47
8
0
0
0
39
0
8
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
16
0
0
0
% I
% Lys:
0
0
24
0
8
0
0
0
0
0
8
8
0
0
0
% K
% Leu:
0
8
16
0
0
0
0
8
8
8
0
0
0
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
16
31
8
0
0
0
0
8
% N
% Pro:
0
8
0
62
16
8
0
0
0
0
0
0
8
0
8
% P
% Gln:
0
8
8
0
0
0
39
8
8
39
8
0
0
0
47
% Q
% Arg:
8
0
39
24
8
0
8
8
0
0
8
0
0
8
0
% R
% Ser:
8
8
0
0
0
8
8
39
8
8
0
8
16
8
0
% S
% Thr:
8
0
0
0
8
0
0
16
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
39
8
16
8
24
0
0
0
16
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
16
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _