KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
9.09
Human Site:
S549
Identified Species:
16.67
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
S549
N
R
K
L
A
V
G
S
H
P
L
P
P
K
I
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
S549
N
R
K
L
A
V
G
S
H
P
L
P
P
K
I
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
P297
P
Q
V
K
V
P
L
P
S
T
D
A
S
N
Q
Dog
Lupus familis
XP_544039
1169
129817
S564
N
R
K
L
V
V
G
S
H
L
P
P
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
I543
N
R
K
L
I
S
G
I
H
P
P
P
Q
K
L
Rat
Rattus norvegicus
NP_001100916
1152
128233
I548
N
R
K
L
I
S
G
I
H
P
P
P
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
P354
G
D
L
P
V
E
K
P
E
R
P
S
P
S
P
Chicken
Gallus gallus
XP_426541
1160
128454
T553
H
L
G
N
Y
Q
T
T
S
K
M
Q
Q
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
V543
E
Q
P
Q
R
P
T
V
P
P
P
P
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
N485
S
L
S
G
T
P
T
N
S
P
K
K
S
N
L
Honey Bee
Apis mellifera
XP_623825
843
94051
G291
Q
E
F
V
P
E
I
G
H
T
C
V
L
V
E
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
D592
S
M
I
S
N
R
T
D
T
G
T
E
D
G
G
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
A432
G
S
Q
P
G
S
I
A
A
Q
R
L
K
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
0
73.3
N.A.
60
60
N.A.
6.6
6.6
N.A.
20
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
6.6
73.3
N.A.
66.6
66.6
N.A.
6.6
26.6
N.A.
26.6
N.A.
26.6
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
0
8
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
0
8
0
8
0
8
% D
% Glu:
8
8
0
0
0
16
0
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
8
8
8
0
39
8
0
8
0
0
0
8
8
% G
% His:
8
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
16
0
16
16
0
0
0
0
0
0
16
% I
% Lys:
0
0
39
8
0
0
8
0
0
8
8
8
8
47
0
% K
% Leu:
0
16
8
39
0
0
8
0
0
8
16
8
8
0
24
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
39
0
0
8
8
0
0
8
0
0
0
0
0
16
0
% N
% Pro:
8
0
8
16
8
24
0
16
8
47
39
47
39
8
24
% P
% Gln:
8
16
8
8
0
8
0
0
0
8
0
8
24
0
8
% Q
% Arg:
0
39
0
0
8
8
0
0
0
8
8
0
0
0
0
% R
% Ser:
16
8
8
8
0
24
0
24
24
0
0
8
16
8
0
% S
% Thr:
0
0
0
0
8
0
31
8
8
16
8
0
0
0
0
% T
% Val:
0
0
8
8
24
24
0
8
0
0
0
8
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _