Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDZD8 All Species: 10.61
Human Site: S603 Identified Species: 19.44
UniProt: Q8NEN9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NEN9 NP_776152.1 1154 128563 S603 Q A K V P L P S A D A P N Q A
Chimpanzee Pan troglodytes XP_508062 1154 128529 S603 Q V K V P L P S A D A P N Q A
Rhesus Macaque Macaca mulatta XP_001097578 849 94271 A348 A A S K Q F L A K Q E V A K D
Dog Lupus familis XP_544039 1169 129817 S618 Q V K V P L P S A D P P N Q T
Cat Felis silvestris
Mouse Mus musculus NP_001028394 1147 127721 P596 Q G R V P L P P T D T S A Q A
Rat Rattus norvegicus NP_001100916 1152 128233 P601 Q G R V P L P P T D T S A Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513246 906 100302 T405 A M A K Q P A T K P E L V K D
Chicken Gallus gallus XP_426541 1160 128454 T604 Q I R P T L P T N E T Q N L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689774 1119 125173 E595 Q P N T G N G E K T P K P V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572771 1037 114536 K536 D K D K D K D K D K G K E E V
Honey Bee Apis mellifera XP_623825 843 94051 R342 V K S A V Q R R F I I R V E R
Nematode Worm Caenorhab. elegans NP_001023093 1301 143952 A643 Q K R K N T D A S D L N G E S
Sea Urchin Strong. purpuratus XP_001204380 984 110525 L483 Q Q D N E D R L R N L K R V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 72.4 89.6 N.A. 86.7 86.6 N.A. 55.7 63.7 N.A. 56.4 N.A. 23.2 25.5 23.6 27.8
Protein Similarity: 100 99.7 72.6 92.4 N.A. 91.7 92 N.A. 63.4 76.4 N.A. 70.8 N.A. 41.3 41.6 41.5 46.7
P-Site Identity: 100 93.3 6.6 80 N.A. 53.3 53.3 N.A. 0 26.6 N.A. 6.6 N.A. 0 0 13.3 6.6
P-Site Similarity: 100 93.3 20 80 N.A. 60 60 N.A. 13.3 46.6 N.A. 13.3 N.A. 6.6 6.6 46.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 8 8 0 0 8 16 24 0 16 0 24 0 31 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 16 0 8 8 16 0 8 47 0 0 0 0 16 % D
% Glu: 0 0 0 0 8 0 0 8 0 8 16 0 8 24 0 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 16 0 0 8 0 8 0 0 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 8 8 0 0 0 8 % I
% Lys: 0 24 24 31 0 8 0 8 24 8 0 24 0 16 0 % K
% Leu: 0 0 0 0 0 47 8 8 0 0 16 8 0 8 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 8 8 0 0 8 8 0 8 31 0 0 % N
% Pro: 0 8 0 8 39 8 47 16 0 8 16 24 8 0 0 % P
% Gln: 70 8 0 0 16 8 0 0 0 8 0 8 0 39 0 % Q
% Arg: 0 0 31 0 0 0 16 8 8 0 0 8 8 0 8 % R
% Ser: 0 0 16 0 0 0 0 24 8 0 0 16 0 0 16 % S
% Thr: 0 0 0 8 8 8 0 16 16 8 24 0 0 0 8 % T
% Val: 8 16 0 39 8 0 0 0 0 0 0 8 16 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _