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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
24.85
Human Site:
S967
Identified Species:
45.56
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
S967
G
T
D
L
V
E
P
S
P
K
H
T
P
N
T
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
S967
G
T
D
L
V
E
P
S
P
K
H
T
P
N
T
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
S675
N
T
S
D
N
E
G
S
D
T
E
V
C
G
P
Dog
Lupus familis
XP_544039
1169
129817
S982
G
T
D
L
V
E
P
S
P
K
H
T
P
N
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
S960
G
T
D
L
V
E
P
S
P
K
H
T
P
N
T
Rat
Rattus norvegicus
NP_001100916
1152
128233
S965
G
T
D
L
V
E
P
S
P
K
H
T
P
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
T732
S
D
N
E
S
S
D
T
E
V
C
G
S
N
S
Chicken
Gallus gallus
XP_426541
1160
128454
S970
G
T
E
I
V
E
P
S
P
K
H
T
P
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
P930
E
P
S
P
K
H
T
P
N
T
S
D
N
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
D863
K
R
Q
A
S
N
L
D
I
P
G
I
V
S
S
Honey Bee
Apis mellifera
XP_623825
843
94051
M669
D
T
V
Q
G
A
T
M
M
A
M
K
A
S
I
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
N997
Q
H
L
T
P
P
S
N
L
Q
L
H
S
D
E
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
E810
D
Q
P
S
P
T
R
E
L
G
Q
T
R
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
6.6
86.6
N.A.
0
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
26.6
100
N.A.
6.6
N.A.
13.3
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% C
% Asp:
16
8
39
8
0
0
8
8
8
0
0
8
0
8
0
% D
% Glu:
8
0
8
8
0
54
0
8
8
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
0
0
0
8
0
8
0
0
8
8
8
0
8
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
47
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
8
% I
% Lys:
8
0
0
0
8
0
0
0
0
47
0
8
0
0
0
% K
% Leu:
0
0
8
39
0
0
8
0
16
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% M
% Asn:
8
0
8
0
8
8
0
8
8
0
0
0
8
54
0
% N
% Pro:
0
8
8
8
16
8
47
8
47
8
0
0
47
8
8
% P
% Gln:
8
8
8
8
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
16
8
16
8
8
54
0
0
8
0
16
16
24
% S
% Thr:
0
62
0
8
0
8
16
8
0
16
0
54
0
0
47
% T
% Val:
0
0
8
0
47
0
0
0
0
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _