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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
21.52
Human Site:
S989
Identified Species:
39.44
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
S989
T
E
V
C
G
P
N
S
P
S
K
R
G
N
S
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
S989
T
E
V
C
G
P
N
S
P
S
K
R
G
N
S
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
V697
N
S
T
G
I
K
L
V
R
K
E
G
G
L
D
Dog
Lupus familis
XP_544039
1169
129817
S1004
T
E
V
C
G
P
N
S
P
S
K
R
G
N
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
S982
T
E
V
C
G
S
N
S
P
S
K
R
G
N
S
Rat
Rattus norvegicus
NP_001100916
1152
128233
S987
T
E
V
C
G
P
N
S
P
S
K
R
G
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
K754
T
G
I
K
L
V
R
K
E
G
G
L
D
D
S
Chicken
Gallus gallus
XP_426541
1160
128454
S992
T
E
I
S
G
P
S
S
P
S
K
R
A
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
P952
G
A
S
P
S
K
Q
P
A
G
S
S
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
P885
V
N
S
K
S
L
P
P
S
P
Q
H
T
P
S
Honey Bee
Apis mellifera
XP_623825
843
94051
C691
K
K
A
G
S
T
S
C
L
A
P
P
A
S
G
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
V1019
S
E
L
D
H
P
S
V
T
P
G
D
H
Q
I
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
G832
V
G
V
A
G
R
R
G
T
P
H
P
S
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
100
N.A.
13.3
60
N.A.
6.6
N.A.
6.6
0
13.3
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
100
N.A.
26.6
80
N.A.
13.3
N.A.
13.3
26.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
0
0
8
8
0
0
16
0
0
% A
% Cys:
0
0
0
39
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
8
8
8
8
% D
% Glu:
0
54
0
0
0
0
0
0
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
16
0
16
54
0
0
8
0
16
16
8
54
0
16
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
8
8
0
0
% H
% Ile:
0
0
16
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
0
16
0
16
0
8
0
8
47
0
0
0
8
% K
% Leu:
0
0
8
0
8
8
8
0
8
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
39
0
0
0
0
0
0
39
16
% N
% Pro:
0
0
0
8
0
47
8
16
47
24
8
16
0
16
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
16
0
8
0
0
47
0
0
0
% R
% Ser:
8
8
16
8
24
8
24
47
8
47
8
8
8
24
47
% S
% Thr:
54
0
8
0
0
8
0
0
16
0
0
0
8
0
0
% T
% Val:
16
0
47
0
0
8
0
16
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _