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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
19.7
Human Site:
T1120
Identified Species:
36.11
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
T1120
S
K
K
I
S
K
Y
T
D
D
T
E
E
D
L
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
T1120
S
K
K
I
S
K
Y
T
D
D
T
E
E
D
L
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
D816
K
K
I
S
K
Y
T
D
D
T
E
E
D
L
D
Dog
Lupus familis
XP_544039
1169
129817
T1135
S
K
K
I
S
K
Y
T
D
D
T
E
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
A1113
S
K
K
M
N
K
Y
A
D
D
T
E
E
D
L
Rat
Rattus norvegicus
NP_001100916
1152
128233
T1118
S
K
K
M
N
K
Y
T
E
D
T
E
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
T873
T
S
K
H
P
E
D
T
G
R
A
E
D
P
D
Chicken
Gallus gallus
XP_426541
1160
128454
S1123
S
K
R
V
T
K
D
S
E
E
A
S
I
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
S1079
H
G
F
P
K
A
K
S
E
G
L
E
E
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
P1004
E
K
A
T
E
S
S
P
W
K
S
D
R
S
D
Honey Bee
Apis mellifera
XP_623825
843
94051
D810
I
K
L
I
A
Q
S
D
L
R
V
Q
A
L
S
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
E1245
D
D
D
N
Q
K
R
E
I
T
E
E
I
S
S
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
A951
R
R
R
K
E
K
L
A
L
E
G
A
L
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
20
100
N.A.
80
80
N.A.
20
20
N.A.
20
N.A.
6.6
13.3
13.3
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
100
N.A.
40
60
N.A.
33.3
N.A.
20
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
16
0
0
16
8
8
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
16
16
39
39
0
8
16
39
24
% D
% Glu:
8
0
0
0
16
8
0
8
24
16
16
70
47
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
8
8
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
31
0
0
0
0
8
0
0
0
16
0
0
% I
% Lys:
8
70
47
8
16
62
8
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
8
0
16
0
8
0
8
16
47
% L
% Met:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
8
% Q
% Arg:
8
8
16
0
0
0
8
0
0
16
0
0
8
0
0
% R
% Ser:
47
8
0
8
24
8
16
16
0
0
8
8
0
16
16
% S
% Thr:
8
0
0
8
8
0
8
39
0
16
39
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
39
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _