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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
18.48
Human Site:
T665
Identified Species:
33.89
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
T665
A
K
D
V
T
S
E
T
S
C
P
T
K
D
S
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
T665
A
K
D
V
T
S
E
T
S
C
P
T
K
D
S
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
Y381
W
E
S
S
E
I
L
Y
R
N
K
L
G
K
W
Dog
Lupus familis
XP_544039
1169
129817
S680
T
R
D
F
T
S
E
S
S
C
P
P
K
D
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
S658
V
K
D
L
P
S
E
S
S
A
P
T
K
D
S
Rat
Rattus norvegicus
NP_001100916
1152
128233
S663
V
K
D
A
P
S
E
S
S
A
P
T
K
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
Y438
W
E
S
S
E
V
P
Y
R
N
K
L
G
K
W
Chicken
Gallus gallus
XP_426541
1160
128454
N669
L
K
D
G
I
S
E
N
A
R
G
H
K
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
S630
A
K
D
K
I
S
E
S
S
S
N
T
R
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
V569
P
L
I
H
M
E
D
V
C
S
F
Q
L
D
N
Honey Bee
Apis mellifera
XP_623825
843
94051
D375
K
I
S
A
E
R
G
D
K
K
T
L
K
I
D
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
E702
R
L
K
K
K
L
S
E
S
P
K
I
R
R
A
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
K516
S
A
V
P
M
M
M
K
T
E
A
M
R
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
0
60
N.A.
66.6
60
N.A.
0
40
N.A.
60
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
6.6
73.3
N.A.
80
66.6
N.A.
6.6
46.6
N.A.
73.3
N.A.
20
6.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
0
16
0
0
0
0
8
16
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
24
0
0
0
0
0
% C
% Asp:
0
0
54
0
0
0
8
8
0
0
0
0
0
62
8
% D
% Glu:
0
16
0
0
24
8
54
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
0
8
0
16
0
16
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
8
0
16
8
0
0
0
0
0
8
0
16
0
% I
% Lys:
8
47
8
16
8
0
0
8
8
8
24
0
54
16
0
% K
% Leu:
8
16
0
8
0
8
8
0
0
0
0
24
8
0
0
% L
% Met:
0
0
0
0
16
8
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
16
8
0
0
0
8
% N
% Pro:
8
0
0
8
16
0
8
0
0
8
39
8
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
8
0
0
0
8
0
0
16
8
0
0
24
8
0
% R
% Ser:
8
0
24
16
0
54
8
31
54
16
0
0
0
0
31
% S
% Thr:
8
0
0
0
24
0
0
16
8
0
8
39
0
0
0
% T
% Val:
16
0
8
16
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _