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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDZD8 All Species: 24.55
Human Site: T961 Identified Species: 45
UniProt: Q8NEN9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NEN9 NP_776152.1 1154 128563 T961 T R L S E P G T D L V E P S P
Chimpanzee Pan troglodytes XP_508062 1154 128529 T961 T R L S E P G T D L V E P S P
Rhesus Macaque Macaca mulatta XP_001097578 849 94271 T669 S P K H T P N T S D N E G S D
Dog Lupus familis XP_544039 1169 129817 T976 T R L S E P G T D L V E P S P
Cat Felis silvestris
Mouse Mus musculus NP_001028394 1147 127721 T954 T R L S E P G T D L V E P S P
Rat Rattus norvegicus NP_001100916 1152 128233 T959 T R L A E P G T D L V E P S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513246 906 100302 D726 K H T P N T S D N E S S D T E
Chicken Gallus gallus XP_426541 1160 128454 T964 A R L S E Q G T E I V E P S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689774 1119 125173 P924 M G S G V V E P S P K H T P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572771 1037 114536 R857 M L A Q G I K R Q A S N L D I
Honey Bee Apis mellifera XP_623825 843 94051 T663 S L T S C E D T V Q G A T M M
Nematode Worm Caenorhab. elegans NP_001023093 1301 143952 H991 I A C T P Q Q H L T P P S N L
Sea Urchin Strong. purpuratus XP_001204380 984 110525 Q804 R S A R R A D Q P S P T R E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 72.4 89.6 N.A. 86.7 86.6 N.A. 55.7 63.7 N.A. 56.4 N.A. 23.2 25.5 23.6 27.8
Protein Similarity: 100 99.7 72.6 92.4 N.A. 91.7 92 N.A. 63.4 76.4 N.A. 70.8 N.A. 41.3 41.6 41.5 46.7
P-Site Identity: 100 100 26.6 100 N.A. 100 93.3 N.A. 0 73.3 N.A. 0 N.A. 0 13.3 0 0
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 13.3 86.6 N.A. 0 N.A. 0 20 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 8 0 8 0 0 0 8 0 8 0 0 0 % A
% Cys: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 8 39 8 0 0 8 8 8 % D
% Glu: 0 0 0 0 47 8 8 0 8 8 0 54 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 8 0 47 0 0 0 8 0 8 0 0 % G
% His: 0 8 0 8 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 8 % I
% Lys: 8 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % K
% Leu: 0 16 47 0 0 0 0 0 8 39 0 0 8 0 16 % L
% Met: 16 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % M
% Asn: 0 0 0 0 8 0 8 0 8 0 8 8 0 8 8 % N
% Pro: 0 8 0 8 8 47 0 8 8 8 16 8 47 8 47 % P
% Gln: 0 0 0 8 0 16 8 8 8 8 0 0 0 0 0 % Q
% Arg: 8 47 0 8 8 0 0 8 0 0 0 0 8 0 0 % R
% Ser: 16 8 8 47 0 0 8 0 16 8 16 8 8 54 0 % S
% Thr: 39 0 16 8 8 8 0 62 0 8 0 8 16 8 0 % T
% Val: 0 0 0 0 8 8 0 0 8 0 47 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _