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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
26.06
Human Site:
Y288
Identified Species:
47.78
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
Y288
R
K
H
T
L
P
N
Y
K
I
R
F
K
P
F
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
Y288
R
K
H
T
L
P
N
Y
K
I
R
F
K
P
F
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
E53
L
S
S
S
V
W
E
E
K
Q
R
S
S
I
K
Dog
Lupus familis
XP_544039
1169
129817
Y302
R
K
H
T
L
P
S
Y
K
I
R
F
K
P
F
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
Y287
R
K
H
T
L
P
S
Y
K
I
R
F
K
P
F
Rat
Rattus norvegicus
NP_001100916
1152
128233
Y287
R
K
H
T
L
P
S
Y
K
I
R
F
K
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
L110
G
N
L
Q
S
V
G
L
T
L
R
L
V
Q
S
Chicken
Gallus gallus
XP_426541
1160
128454
Y296
R
K
H
T
L
P
N
Y
K
I
R
Y
K
P
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
T282
V
E
G
R
L
R
V
T
L
V
E
C
S
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
E241
P
E
L
I
L
D
I
E
S
K
Y
Q
G
R
Q
Honey Bee
Apis mellifera
XP_623825
843
94051
T47
K
E
L
L
T
Q
S
T
T
G
K
L
L
D
S
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
Y304
L
D
D
K
N
K
N
Y
E
V
Y
C
T
V
S
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
E188
F
D
I
Q
T
H
F
E
G
R
T
V
H
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
6.6
93.3
N.A.
6.6
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
13.3
100
N.A.
20
N.A.
13.3
26.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
0
16
8
0
0
8
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
24
0
0
0
0
8
24
8
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
0
39
0
0
47
% F
% Gly:
8
0
8
0
0
0
8
0
8
8
0
0
8
0
0
% G
% His:
0
0
47
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
8
0
0
8
0
0
47
0
0
0
8
0
% I
% Lys:
8
47
0
8
0
8
0
0
54
8
8
0
47
0
8
% K
% Leu:
16
0
24
8
62
0
0
8
8
8
0
16
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
31
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
47
0
0
0
0
0
0
0
47
0
% P
% Gln:
0
0
0
16
0
8
0
0
0
8
0
8
0
16
8
% Q
% Arg:
47
0
0
8
0
8
0
0
0
8
62
0
0
16
0
% R
% Ser:
0
8
8
8
8
0
31
0
8
0
0
8
16
0
24
% S
% Thr:
0
0
0
47
16
0
0
16
16
0
8
0
8
0
0
% T
% Val:
8
0
0
0
8
8
8
0
0
16
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
16
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _