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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD8
All Species:
19.09
Human Site:
Y751
Identified Species:
35
UniProt:
Q8NEN9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEN9
NP_776152.1
1154
128563
Y751
L
A
T
S
N
T
E
Y
L
S
K
L
R
L
E
Chimpanzee
Pan troglodytes
XP_508062
1154
128529
Y751
L
A
T
S
N
T
E
Y
L
S
K
L
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001097578
849
94271
A459
L
E
A
P
S
P
K
A
I
V
T
R
T
A
L
Dog
Lupus familis
XP_544039
1169
129817
Y766
L
A
T
S
N
M
E
Y
F
S
K
F
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028394
1147
127721
Y744
L
A
T
S
N
M
E
Y
L
T
K
F
R
L
E
Rat
Rattus norvegicus
NP_001100916
1152
128233
Y749
L
A
T
S
N
M
E
Y
L
S
K
F
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513246
906
100302
A516
L
D
A
P
V
P
K
A
I
V
S
R
T
A
L
Chicken
Gallus gallus
XP_426541
1160
128454
M754
D
C
I
A
T
S
S
M
E
Y
V
R
T
F
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689774
1119
125173
Y714
I
S
T
S
S
A
E
Y
Q
S
T
F
R
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572771
1037
114536
L647
Q
S
G
F
N
P
N
L
C
F
G
D
I
L
F
Honey Bee
Apis mellifera
XP_623825
843
94051
I453
E
E
T
R
T
F
Q
I
D
S
E
L
Q
Y
L
Nematode Worm
Caenorhab. elegans
NP_001023093
1301
143952
A781
A
G
T
P
T
T
S
A
T
N
V
P
N
A
T
Sea Urchin
Strong. purpuratus
XP_001204380
984
110525
D594
P
F
Q
V
G
E
N
D
N
F
L
N
V
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
89.6
N.A.
86.7
86.6
N.A.
55.7
63.7
N.A.
56.4
N.A.
23.2
25.5
23.6
27.8
Protein Similarity:
100
99.7
72.6
92.4
N.A.
91.7
92
N.A.
63.4
76.4
N.A.
70.8
N.A.
41.3
41.6
41.5
46.7
P-Site Identity:
100
100
6.6
80
N.A.
80
86.6
N.A.
6.6
0
N.A.
46.6
N.A.
13.3
20
13.3
0
P-Site Similarity:
100
100
26.6
80
N.A.
86.6
86.6
N.A.
20
20
N.A.
66.6
N.A.
20
40
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
16
8
0
8
0
24
0
0
0
0
0
24
0
% A
% Cys:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
8
% C
% Asp:
8
8
0
0
0
0
0
8
8
0
0
8
0
0
0
% D
% Glu:
8
16
0
0
0
8
47
0
8
0
8
0
0
0
39
% E
% Phe:
0
8
0
8
0
8
0
0
8
16
0
31
0
8
8
% F
% Gly:
0
8
8
0
8
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
16
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
16
0
0
0
39
0
0
0
8
% K
% Leu:
54
0
0
0
0
0
0
8
31
0
8
24
0
54
24
% L
% Met:
0
0
0
0
0
24
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
47
0
16
0
8
8
0
8
8
0
0
% N
% Pro:
8
0
0
24
0
24
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
0
8
0
0
0
8
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
24
47
0
0
% R
% Ser:
0
16
0
47
16
8
16
0
0
47
8
0
0
0
0
% S
% Thr:
0
0
62
0
24
24
0
0
8
8
16
0
24
0
8
% T
% Val:
0
0
0
8
8
0
0
0
0
16
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _