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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC50 All Species: 8.79
Human Site: S686 Identified Species: 21.48
UniProt: Q8NEP3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NEP3 NP_848547.4 725 80026 S686 D S D F L A A S S P V P T E S
Chimpanzee Pan troglodytes XP_511137 725 80181 S686 D S D F L A A S S P V P T E S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536764 762 84049 L724 S E D G D S D L L P A S S P E
Cat Felis silvestris
Mouse Mus musculus Q9D2H9 634 69685 Q596 E D G D S D S Q L P A A T L L
Rat Rattus norvegicus Q6AYH9 633 69937 Q595 S S E G G D S Q L P A A T P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516863 630 71015 M592 K I R I R Q A M A S K P I I Q
Chicken Gallus gallus XP_414069 621 70519 K583 S P W E E E R K I T I A C S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7ZV84 555 62127 T517 Q Q L I S V S T T R N S V K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393975 1711 194833 S1260 E S A K V S S S T N I V E K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782591 513 58706 E475 P S R P L V E E L G P V S D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 58.5 N.A. 56.9 57.3 N.A. 39.4 40.6 N.A. 35 N.A. N.A. 21.3 N.A. 31.4
Protein Similarity: 100 98.4 N.A. 66.9 N.A. 65.6 67 N.A. 55 54.2 N.A. 49.5 N.A. N.A. 29.9 N.A. 46.4
P-Site Identity: 100 100 N.A. 13.3 N.A. 13.3 20 N.A. 13.3 0 N.A. 0 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 100 N.A. 26.6 N.A. 26.6 33.3 N.A. 20 6.6 N.A. 26.6 N.A. N.A. 66.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 20 30 0 10 0 30 30 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 20 10 30 10 10 20 10 0 0 0 0 0 0 10 0 % D
% Glu: 20 10 10 10 10 10 10 10 0 0 0 0 10 20 10 % E
% Phe: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 20 10 0 0 0 0 10 0 0 0 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 20 0 0 0 0 10 0 20 0 10 10 0 % I
% Lys: 10 0 0 10 0 0 0 10 0 0 10 0 0 20 0 % K
% Leu: 0 0 10 0 30 0 0 10 40 0 0 0 0 10 20 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % N
% Pro: 10 10 0 10 0 0 0 0 0 50 10 30 0 20 0 % P
% Gln: 10 10 0 0 0 10 0 20 0 0 0 0 0 0 20 % Q
% Arg: 0 0 20 0 10 0 10 0 0 10 0 0 0 0 0 % R
% Ser: 30 50 0 0 20 20 40 30 20 10 0 20 20 10 30 % S
% Thr: 0 0 0 0 0 0 0 10 20 10 0 0 40 0 0 % T
% Val: 0 0 0 0 10 20 0 0 0 0 20 20 10 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _