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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVR1C
All Species:
32.12
Human Site:
T166
Identified Species:
70.67
UniProt:
Q8NER5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NER5
NP_001104501.1
493
54871
T166
N
L
V
N
A
G
K
T
L
K
D
L
I
Y
D
Chimpanzee
Pan troglodytes
XP_525945
493
54826
T166
N
L
V
N
A
G
K
T
L
K
D
L
I
Y
D
Rhesus Macaque
Macaca mulatta
XP_001088578
493
54866
T166
N
L
V
N
A
G
K
T
L
K
D
L
I
Y
D
Dog
Lupus familis
XP_545483
494
54831
T167
A
L
V
G
A
G
K
T
L
Q
D
L
I
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K348
493
54666
T166
S
L
V
N
A
G
K
T
L
K
D
L
I
Y
D
Rat
Rattus norvegicus
P70539
493
54824
T166
S
L
V
N
A
G
K
T
L
K
D
L
I
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512345
505
55810
T178
N
L
V
N
A
G
K
T
L
K
D
L
I
Y
D
Chicken
Gallus gallus
Q05438
502
56748
S175
T
Y
I
P
P
G
E
S
L
K
D
L
I
E
Q
Frog
Xenopus laevis
P27041
511
57917
N172
S
Y
G
H
V
E
I
N
E
D
P
G
L
P
P
Zebra Danio
Brachydanio rerio
NP_571065
505
56615
T178
L
Y
L
A
K
D
K
T
L
Q
D
L
I
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20792
669
74988
V270
N
M
K
D
M
L
D
V
L
E
E
T
S
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
88.8
N.A.
92.6
92.4
N.A.
85.5
50.2
29.5
63.5
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
100
99.8
99.5
92.3
N.A.
96.5
96.3
N.A.
92.4
65.5
45.5
77.2
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
100
40
0
46.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
100
60
20
66.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
64
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
10
0
10
10
0
0
10
82
0
0
0
73
% D
% Glu:
0
0
0
0
0
10
10
0
10
10
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
10
0
73
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
82
0
0
% I
% Lys:
0
0
10
0
10
0
73
0
0
64
0
0
0
0
0
% K
% Leu:
10
64
10
0
0
10
0
0
91
0
0
82
10
0
0
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
46
0
0
55
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
0
0
0
10
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
28
0
0
0
0
0
0
10
0
0
0
0
10
0
10
% S
% Thr:
10
0
0
0
0
0
0
73
0
0
0
10
0
0
0
% T
% Val:
0
0
64
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
28
0
0
0
0
0
0
0
0
0
0
0
55
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _