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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1C2
All Species:
14.85
Human Site:
S316
Identified Species:
25.13
UniProt:
Q8NEY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEY4
NP_001034451.1
427
48759
S316
Q
T
D
R
E
R
E
S
E
G
E
G
E
G
P
Chimpanzee
Pan troglodytes
XP_519896
355
40662
Q252
K
F
I
V
R
D
F
Q
Y
N
E
E
E
M
K
Rhesus Macaque
Macaca mulatta
XP_001095057
415
47283
R312
P
A
A
G
Q
T
D
R
E
R
E
S
E
G
E
Dog
Lupus familis
XP_856922
427
48544
S316
Q
T
D
R
E
R
E
S
E
G
E
G
E
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99L60
427
48332
S316
Q
T
D
R
D
R
E
S
E
G
E
G
E
G
P
Rat
Rattus norvegicus
Q6AYE4
425
48225
G316
Q
N
D
R
E
S
E
G
E
G
E
G
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505973
426
48296
S316
Q
T
E
R
E
R
E
S
E
G
E
G
E
G
P
Chicken
Gallus gallus
XP_419951
382
43705
L279
K
Q
Q
Y
G
P
L
L
R
W
L
K
V
N
F
Frog
Xenopus laevis
Q5XH14
382
43976
L279
K
K
K
Q
F
G
P
L
V
R
W
L
K
V
N
Zebra Danio
Brachydanio rerio
Q7T385
383
44296
V280
K
K
Q
F
G
P
L
V
R
W
L
K
V
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7N5
836
92372
T552
A
E
L
P
Q
Y
L
T
R
F
Q
W
D
M
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXU9
384
43440
P280
E
K
Q
R
Q
Y
A
P
L
I
R
W
L
K
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDS7
375
42601
E272
A
K
L
V
Q
D
Q
E
S
L
R
S
S
L
L
Baker's Yeast
Sacchar. cerevisiae
P31412
392
44170
V289
Q
S
L
R
V
Q
L
V
R
L
A
K
T
A
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.9
92.9
95
N.A.
91.8
92
N.A.
86.8
68.8
56.2
57.8
N.A.
24.2
N.A.
45.4
N.A.
Protein Similarity:
100
69.7
94.8
98.1
N.A.
95.3
95.5
N.A.
94.3
81
74.4
75.8
N.A.
36.9
N.A.
65.8
N.A.
P-Site Identity:
100
13.3
26.6
100
N.A.
93.3
60
N.A.
93.3
0
0
0
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
20
40
100
N.A.
100
60
N.A.
100
6.6
20
6.6
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.2
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
0
0
0
8
0
0
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
29
0
8
15
8
0
0
0
0
0
8
0
0
% D
% Glu:
8
8
8
0
29
0
36
8
43
0
50
8
43
0
8
% E
% Phe:
0
8
0
8
8
0
8
0
0
8
0
0
0
0
15
% F
% Gly:
0
0
0
8
15
8
0
8
0
36
0
36
0
36
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
29
29
8
0
0
0
0
0
0
0
0
22
8
8
8
% K
% Leu:
0
0
22
0
0
0
29
15
8
15
15
8
8
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
15
8
% N
% Pro:
8
0
0
8
0
15
8
8
0
0
0
0
8
0
29
% P
% Gln:
43
8
22
8
29
8
8
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
50
8
29
0
8
29
15
15
0
0
0
0
% R
% Ser:
0
8
0
0
0
8
0
29
8
0
0
15
8
0
0
% S
% Thr:
0
29
0
0
0
8
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
15
8
0
0
15
8
0
0
0
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
15
8
15
0
0
0
% W
% Tyr:
0
0
0
8
0
15
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _