KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1C2
All Species:
8.48
Human Site:
T246
Identified Species:
14.36
UniProt:
Q8NEY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEY4
NP_001034451.1
427
48759
T246
K
A
K
E
N
K
F
T
V
R
E
F
Y
Y
D
Chimpanzee
Pan troglodytes
XP_519896
355
40662
T184
L
D
S
E
Y
L
V
T
L
L
V
V
V
P
K
Rhesus Macaque
Macaca mulatta
XP_001095057
415
47283
K244
K
T
K
A
K
E
N
K
F
T
V
R
E
F
Y
Dog
Lupus familis
XP_856922
427
48544
T246
K
A
K
E
N
K
F
T
V
R
E
F
Y
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99L60
427
48332
I246
K
A
K
E
N
K
F
I
V
R
E
F
Y
Y
D
Rat
Rattus norvegicus
Q6AYE4
425
48225
I246
K
A
K
E
N
K
F
I
V
R
E
F
Y
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505973
426
48296
I246
K
A
K
E
N
K
F
I
V
R
E
F
F
Y
D
Chicken
Gallus gallus
XP_419951
382
43705
S211
S
D
M
V
V
P
R
S
T
K
M
I
A
E
D
Frog
Xenopus laevis
Q5XH14
382
43976
R211
L
S
E
M
V
V
P
R
S
S
N
V
L
S
E
Zebra Danio
Brachydanio rerio
Q7T385
383
44296
S212
A
E
M
V
V
P
R
S
T
N
L
L
F
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7N5
836
92372
A432
A
Q
Q
Q
H
E
T
A
Q
L
Q
H
Q
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXU9
384
43440
P212
T
L
S
S
M
V
V
P
G
S
S
K
L
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDS7
375
42601
T204
L
A
C
Y
E
T
L
T
D
Y
V
V
P
R
S
Baker's Yeast
Sacchar. cerevisiae
P31412
392
44170
S221
S
K
N
V
V
P
A
S
A
S
V
I
A
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.9
92.9
95
N.A.
91.8
92
N.A.
86.8
68.8
56.2
57.8
N.A.
24.2
N.A.
45.4
N.A.
Protein Similarity:
100
69.7
94.8
98.1
N.A.
95.3
95.5
N.A.
94.3
81
74.4
75.8
N.A.
36.9
N.A.
65.8
N.A.
P-Site Identity:
100
13.3
13.3
100
N.A.
93.3
93.3
N.A.
86.6
6.6
0
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
20
26.6
100
N.A.
93.3
93.3
N.A.
93.3
20
20
20
N.A.
33.3
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.2
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
43
0
8
0
0
8
8
8
0
0
0
15
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
8
0
0
0
0
0
58
% D
% Glu:
0
8
8
43
8
15
0
0
0
0
36
0
8
22
8
% E
% Phe:
0
0
0
0
0
0
36
0
8
0
0
36
15
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
22
0
0
0
15
0
0
0
% I
% Lys:
43
8
43
0
8
36
0
8
0
8
0
8
0
0
8
% K
% Leu:
22
8
0
0
0
8
8
0
8
15
8
8
15
8
0
% L
% Met:
0
0
15
8
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
36
0
8
0
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
22
8
8
0
0
0
0
8
8
0
% P
% Gln:
0
8
8
8
0
0
0
0
8
0
8
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
15
8
0
36
0
8
0
8
0
% R
% Ser:
15
8
15
8
0
0
0
22
8
22
8
0
0
8
8
% S
% Thr:
8
8
0
0
0
8
8
29
15
8
0
0
0
0
15
% T
% Val:
0
0
0
22
29
15
15
0
36
0
29
22
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
8
0
0
29
36
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _