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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1C2
All Species:
15.76
Human Site:
T288
Identified Species:
26.67
UniProt:
Q8NEY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEY4
NP_001034451.1
427
48759
T288
A
L
K
K
G
S
S
T
F
P
D
H
K
V
K
Chimpanzee
Pan troglodytes
XP_519896
355
40662
L224
S
E
D
Q
D
S
Y
L
C
N
V
T
L
F
R
Rhesus Macaque
Macaca mulatta
XP_001095057
415
47283
K284
T
S
C
V
A
L
K
K
G
S
S
T
F
P
D
Dog
Lupus familis
XP_856922
427
48544
T288
A
L
K
K
G
S
S
T
F
L
D
H
K
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99L60
427
48332
T288
A
L
K
K
G
S
A
T
Y
R
D
H
K
V
K
Rat
Rattus norvegicus
Q6AYE4
425
48225
T288
A
L
K
K
G
S
A
T
Y
R
D
H
K
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505973
426
48296
A288
A
L
K
K
G
S
A
A
L
P
D
H
M
V
K
Chicken
Gallus gallus
XP_419951
382
43705
Y251
R
F
M
V
R
E
F
Y
F
D
E
K
E
L
K
Frog
Xenopus laevis
Q5XH14
382
43976
F251
N
K
F
V
V
R
D
F
Q
Y
N
E
E
E
M
Zebra Danio
Brachydanio rerio
Q7T385
383
44296
Q252
K
F
T
V
R
D
F
Q
Y
N
E
E
E
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7N5
836
92372
S524
S
S
C
C
G
S
S
S
Q
G
R
S
S
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXU9
384
43440
D252
E
N
K
F
I
V
R
D
F
V
Y
D
E
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDS7
375
42601
G244
R
I
A
A
R
E
K
G
F
Q
V
R
D
F
E
Baker's Yeast
Sacchar. cerevisiae
P31412
392
44170
N261
K
F
I
P
R
E
F
N
Y
S
E
E
L
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.9
92.9
95
N.A.
91.8
92
N.A.
86.8
68.8
56.2
57.8
N.A.
24.2
N.A.
45.4
N.A.
Protein Similarity:
100
69.7
94.8
98.1
N.A.
95.3
95.5
N.A.
94.3
81
74.4
75.8
N.A.
36.9
N.A.
65.8
N.A.
P-Site Identity:
100
6.6
0
93.3
N.A.
80
80
N.A.
73.3
13.3
0
6.6
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
0
93.3
N.A.
93.3
93.3
N.A.
80
33.3
13.3
33.3
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.2
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
8
8
8
0
22
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
15
8
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
8
8
8
0
8
36
8
8
0
22
% D
% Glu:
8
8
0
0
0
22
0
0
0
0
22
22
29
15
8
% E
% Phe:
0
22
8
8
0
0
22
8
36
0
0
0
8
15
0
% F
% Gly:
0
0
0
0
43
0
0
8
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% H
% Ile:
0
8
8
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
15
8
43
36
0
0
15
8
0
0
0
8
29
0
50
% K
% Leu:
0
36
0
0
0
8
0
8
8
8
0
0
15
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
8
% M
% Asn:
8
8
0
0
0
0
0
8
0
15
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
15
0
0
0
15
0
% P
% Gln:
0
0
0
8
0
0
0
8
15
8
0
0
0
0
0
% Q
% Arg:
15
0
0
0
29
8
8
0
0
15
8
8
0
0
8
% R
% Ser:
15
15
0
0
0
50
22
8
0
15
8
8
8
0
0
% S
% Thr:
8
0
8
0
0
0
0
29
0
0
0
15
0
0
8
% T
% Val:
0
0
0
29
8
8
0
0
0
8
15
0
0
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
29
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _