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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1C2
All Species:
15.15
Human Site:
Y193
Identified Species:
25.64
UniProt:
Q8NEY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEY4
NP_001034451.1
427
48759
Y193
V
I
V
P
K
P
N
Y
S
Q
W
Q
K
T
Y
Chimpanzee
Pan troglodytes
XP_519896
355
40662
Q131
I
I
A
K
G
V
T
Q
I
D
N
D
L
K
S
Rhesus Macaque
Macaca mulatta
XP_001095057
415
47283
S191
L
L
V
I
V
P
K
S
N
Y
S
Q
W
Q
K
Dog
Lupus familis
XP_856922
427
48544
Y193
V
I
V
P
K
P
S
Y
T
Q
W
Q
K
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99L60
427
48332
F193
V
I
V
P
K
S
S
F
A
Q
W
Q
K
T
Y
Rat
Rattus norvegicus
Q6AYE4
425
48225
Y193
V
I
V
P
K
S
S
Y
V
Q
W
Q
K
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505973
426
48296
Y193
V
I
V
P
K
T
S
Y
A
Q
W
Q
K
T
Y
Chicken
Gallus gallus
XP_419951
382
43705
G158
N
L
E
K
K
T
V
G
N
L
L
T
R
T
L
Frog
Xenopus laevis
Q5XH14
382
43976
A158
Q
N
L
E
R
K
N
A
G
S
L
I
T
R
S
Zebra Danio
Brachydanio rerio
Q7T385
383
44296
G159
N
L
E
R
K
N
A
G
S
L
L
T
R
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7N5
836
92372
E379
Q
K
S
M
S
E
D
E
G
D
A
S
N
A
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXU9
384
43440
T159
L
A
S
M
D
R
K
T
V
G
S
L
L
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDS7
375
42601
N151
N
N
I
R
G
Q
L
N
A
I
N
R
K
Q
S
Baker's Yeast
Sacchar. cerevisiae
P31412
392
44170
G168
A
A
E
R
K
K
T
G
D
L
S
V
R
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.9
92.9
95
N.A.
91.8
92
N.A.
86.8
68.8
56.2
57.8
N.A.
24.2
N.A.
45.4
N.A.
Protein Similarity:
100
69.7
94.8
98.1
N.A.
95.3
95.5
N.A.
94.3
81
74.4
75.8
N.A.
36.9
N.A.
65.8
N.A.
P-Site Identity:
100
6.6
20
86.6
N.A.
73.3
80
N.A.
80
13.3
6.6
13.3
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
40
100
N.A.
93.3
86.6
N.A.
93.3
33.3
20
33.3
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.2
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
0
0
8
8
22
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
8
15
0
8
0
0
0
% D
% Glu:
0
0
22
8
0
8
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
22
15
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
43
8
8
0
0
0
0
8
8
0
8
0
0
0
% I
% Lys:
0
8
0
15
58
15
15
0
0
0
0
0
43
8
15
% K
% Leu:
15
22
8
0
0
0
8
0
0
22
22
8
15
0
22
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
15
0
0
0
8
15
8
15
0
15
0
8
0
0
% N
% Pro:
0
0
0
36
0
22
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
8
0
8
0
36
0
43
0
15
0
% Q
% Arg:
0
0
0
22
8
8
0
0
0
0
0
8
22
8
0
% R
% Ser:
0
0
15
0
8
15
29
8
15
8
22
8
0
15
22
% S
% Thr:
0
0
0
0
0
15
15
8
8
0
0
15
8
50
0
% T
% Val:
36
0
43
0
8
8
8
0
15
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
36
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
8
0
0
0
0
36
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _