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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLL3
All Species:
16.36
Human Site:
T3298
Identified Species:
60
UniProt:
Q8NEZ4
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEZ4
NP_733751.2
4911
541370
T3298
I
P
G
A
T
P
P
T
M
S
Q
P
T
F
P
Chimpanzee
Pan troglodytes
XP_519508
4802
529408
T3240
I
P
G
A
T
P
P
T
M
S
Q
P
A
F
P
Rhesus Macaque
Macaca mulatta
XP_001107669
4824
532391
T3090
I
P
G
A
T
P
P
T
M
S
Q
P
S
F
P
Dog
Lupus familis
XP_853821
1445
159157
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH4
4903
540168
T3294
V
P
G
A
T
S
L
T
M
S
Q
P
N
F
P
Rat
Rattus norvegicus
XP_002726356
4931
542751
T3319
V
P
G
A
S
P
L
T
M
S
Q
P
N
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRW8
2431
259810
Q970
Q
L
Q
P
S
P
H
Q
V
K
Q
T
V
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
92.2
26.2
N.A.
85.3
84.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
21
N.A.
N.A.
N.A.
Protein Similarity:
100
95.5
93.1
27.5
N.A.
90.7
89.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.9
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
0
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
72
0
0
0
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% F
% Gly:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% K
% Leu:
0
15
0
0
0
0
29
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% N
% Pro:
0
72
0
15
0
72
43
0
0
0
0
72
0
0
72
% P
% Gln:
15
0
15
0
0
0
0
15
0
0
86
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
29
15
0
0
0
72
0
0
15
0
0
% S
% Thr:
0
0
0
0
58
0
0
72
0
0
0
15
15
0
0
% T
% Val:
29
0
0
0
0
0
0
0
15
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _