KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO22
All Species:
22.12
Human Site:
T289
Identified Species:
69.52
UniProt:
Q8NEZ5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEZ5
NP_036302.1
403
44508
T289
G
H
R
I
Q
S
A
T
V
L
L
N
E
D
V
Chimpanzee
Pan troglodytes
XP_001145977
403
44575
T289
G
H
R
I
Q
S
A
T
V
L
L
N
E
D
V
Rhesus Macaque
Macaca mulatta
XP_001104297
404
44635
T290
G
H
R
I
Q
S
A
T
V
L
L
N
E
D
V
Dog
Lupus familis
XP_544796
401
44104
T287
G
H
R
I
Q
S
A
T
V
L
L
N
E
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q78JE5
402
44184
T288
G
H
R
I
Q
S
A
T
V
L
L
T
E
D
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025716
393
43238
T276
G
P
Q
I
Q
S
A
T
V
L
L
D
Q
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025277
385
42124
L279
K
V
Q
G
A
S
V
L
V
E
Q
D
V
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122526
367
41988
W262
I
V
G
S
V
D
S
W
S
I
V
M
D
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.7
88
N.A.
92.3
N.A.
N.A.
N.A.
66.2
N.A.
48.8
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
100
99.7
98
92.3
N.A.
95
N.A.
N.A.
N.A.
80.1
N.A.
63.7
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
73.3
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
N.A.
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
75
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
0
0
25
13
75
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
13
0
0
63
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
75
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
13
0
75
75
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
25
0
75
0
0
0
0
0
13
0
13
0
0
% Q
% Arg:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
0
88
13
0
13
0
0
0
0
13
13
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
0
13
0
0
13
% T
% Val:
0
25
0
0
13
0
13
0
88
0
13
0
13
0
75
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _