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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM185A
All Species:
20.61
Human Site:
S333
Identified Species:
64.76
UniProt:
Q8NFB2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFB2
NP_115897.1
350
40647
S333
A
R
V
V
I
T
Q
S
P
G
K
Y
V
L
P
Chimpanzee
Pan troglodytes
XP_525903
350
40581
S333
A
R
V
V
I
T
Q
S
P
G
K
Y
V
P
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853062
350
40640
S333
T
R
V
V
I
T
Q
S
P
G
K
Y
V
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3R5
350
40683
S333
A
R
V
V
I
T
Q
S
P
G
K
Y
V
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512605
467
52814
S450
T
R
V
V
I
T
Q
S
P
G
K
Y
V
I
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SYC7
351
40665
S334
T
G
V
V
I
T
Q
S
P
G
K
Y
F
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396742
339
39216
K327
V
K
K
I
D
L
T
K
P
V
V
P
I
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203000
345
39695
K333
K
Q
A
M
L
D
Y
K
V
V
M
P
V
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99.1
N.A.
88
N.A.
N.A.
73.6
N.A.
N.A.
87.7
N.A.
N.A.
52.5
N.A.
54.5
Protein Similarity:
100
95.1
N.A.
99.7
N.A.
94.5
N.A.
N.A.
74.7
N.A.
N.A.
93.7
N.A.
N.A.
70.8
N.A.
74.5
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
93.3
N.A.
N.A.
86.6
N.A.
N.A.
73.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
N.A.
N.A.
93.3
N.A.
N.A.
80
N.A.
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
0
75
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
75
0
0
0
0
0
0
0
13
38
0
% I
% Lys:
13
13
13
0
0
0
0
25
0
0
75
0
0
0
0
% K
% Leu:
0
0
0
0
13
13
0
0
0
0
0
0
0
25
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
88
0
0
25
0
25
75
% P
% Gln:
0
13
0
0
0
0
75
0
0
0
0
0
0
0
0
% Q
% Arg:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
25
% S
% Thr:
38
0
0
0
0
75
13
0
0
0
0
0
0
0
0
% T
% Val:
13
0
75
75
0
0
0
0
13
25
13
0
75
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
75
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _