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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM185A
All Species:
12.73
Human Site:
T310
Identified Species:
40
UniProt:
Q8NFB2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFB2
NP_115897.1
350
40647
T310
D
N
E
E
T
E
E
T
P
V
P
E
P
P
K
Chimpanzee
Pan troglodytes
XP_525903
350
40581
T310
D
S
E
D
A
E
E
T
S
V
P
E
A
P
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853062
350
40640
T310
D
N
E
E
T
E
E
T
P
V
P
E
P
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3R5
350
40683
A310
D
S
E
D
A
E
D
A
S
V
S
E
A
P
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512605
467
52814
T427
D
N
E
E
T
E
E
T
P
V
P
E
P
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SYC7
351
40665
L311
D
S
D
M
S
E
E
L
P
I
H
E
V
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396742
339
39216
P310
Q
D
Q
P
P
S
E
P
M
V
S
E
K
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203000
345
39695
E316
D
Q
E
P
E
E
Q
E
I
Q
R
E
I
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99.1
N.A.
88
N.A.
N.A.
73.6
N.A.
N.A.
87.7
N.A.
N.A.
52.5
N.A.
54.5
Protein Similarity:
100
95.1
N.A.
99.7
N.A.
94.5
N.A.
N.A.
74.7
N.A.
N.A.
93.7
N.A.
N.A.
70.8
N.A.
74.5
P-Site Identity:
100
66.6
N.A.
100
N.A.
46.6
N.A.
N.A.
100
N.A.
N.A.
46.6
N.A.
N.A.
20
N.A.
26.6
P-Site Similarity:
100
80
N.A.
100
N.A.
66.6
N.A.
N.A.
100
N.A.
N.A.
73.3
N.A.
N.A.
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
0
13
0
0
0
0
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
88
13
13
25
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
75
38
13
88
75
13
0
0
0
100
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
13
0
0
13
0
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
75
% K
% Leu:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% L
% Met:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
38
0
0
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
25
13
0
0
13
50
0
50
0
38
75
0
% P
% Gln:
13
13
13
0
0
0
13
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% R
% Ser:
0
38
0
0
13
13
0
0
25
0
25
0
0
0
0
% S
% Thr:
0
0
0
0
38
0
0
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
75
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _