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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A4 All Species: 18.48
Human Site: S270 Identified Species: 33.89
UniProt: Q8NFF2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFF2 NP_705932.1 605 66951 S270 D G S Y D D P S V P L L G Q V
Chimpanzee Pan troglodytes XP_522932 563 62599 F262 S S P P K F T F P E A G L R I
Rhesus Macaque Macaca mulatta XP_001093277 605 67003 S270 D G S Y D D P S V P L L R Q V
Dog Lupus familis XP_849226 624 68454 S289 D S S S D D P S V P L L G P V
Cat Felis silvestris
Mouse Mus musculus Q8CGQ8 605 66848 S270 D G S Y D D P S V P L L G Q V
Rat Rattus norvegicus Q9EPQ0 624 69371 C272 E I D D S S N C D A T V V L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514620 619 69603 S288 D I S Y D D P S V P L L W E V
Chicken Gallus gallus Q9IAL7 651 72677 L324 G D K D D Q T L T T K P R L Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 Y222 L L L V Y G V Y V A V L C F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN12 642 70657 V314 G S Y T Q E S V G Q T Q G Q K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34322 672 74805 S275 R S R K S I H S V A P M P V I
Sea Urchin Strong. purpuratus XP_780438 570 63240 I249 I I M C F D I I T P L N A T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJI2 643 70138 G336 I E T E T E D G P P R L Q S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.9 98.8 87.6 N.A. 94.3 59.6 N.A. 81.7 36.5 N.A. 35.8 N.A. 33.4 N.A. 22.9 46.4
Protein Similarity: 100 92 99.5 91.5 N.A. 97.1 73.4 N.A. 88.5 52 N.A. 53.2 N.A. 52.4 N.A. 42.7 62.6
P-Site Identity: 100 0 93.3 80 N.A. 100 0 N.A. 80 6.6 N.A. 13.3 N.A. 13.3 N.A. 13.3 20
P-Site Similarity: 100 13.3 93.3 80 N.A. 100 20 N.A. 86.6 6.6 N.A. 20 N.A. 20 N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 24 8 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 8 0 0 0 0 8 0 0 % C
% Asp: 39 8 8 16 47 47 8 0 8 0 0 0 0 0 8 % D
% Glu: 8 8 0 8 0 16 0 0 0 8 0 0 0 8 8 % E
% Phe: 0 0 0 0 8 8 0 8 0 0 0 0 0 8 0 % F
% Gly: 16 24 0 0 0 8 0 8 8 0 0 8 31 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 16 24 0 0 0 8 8 8 0 0 0 0 0 0 16 % I
% Lys: 0 0 8 8 8 0 0 0 0 0 8 0 0 0 8 % K
% Leu: 8 8 8 0 0 0 0 8 0 0 47 54 8 16 16 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 8 8 0 0 39 0 16 54 8 8 8 8 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 8 0 8 8 31 8 % Q
% Arg: 8 0 8 0 0 0 0 0 0 0 8 0 16 8 0 % R
% Ser: 8 31 39 8 16 8 8 47 0 0 0 0 0 8 0 % S
% Thr: 0 0 8 8 8 0 16 0 16 8 16 0 0 8 0 % T
% Val: 0 0 0 8 0 0 8 8 54 0 8 8 8 8 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 8 31 8 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _