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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A4 All Species: 20
Human Site: S399 Identified Species: 36.67
UniProt: Q8NFF2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFF2 NP_705932.1 605 66951 S399 A D F L S P F S V P E A R G D
Chimpanzee Pan troglodytes XP_522932 563 62599 S357 A D F L S P F S M P E A R G D
Rhesus Macaque Macaca mulatta XP_001093277 605 67003 S399 A A F L S P F S M P E A R G D
Dog Lupus familis XP_849226 624 68454 S418 V A F L S P F S V P E A R G D
Cat Felis silvestris
Mouse Mus musculus Q8CGQ8 605 66848 S399 T V F L S P F S M P E A K G D
Rat Rattus norvegicus Q9EPQ0 624 69371 D420 E G P Y T P F D P P S G K L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514620 619 69603 S413 N T F L S P F S M P E A G L E
Chicken Gallus gallus Q9IAL7 651 72677 A452 E D Q P L S L A W P D T P R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 L316 F S M P D H D L K R I L W V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN12 642 70657 P438 R R D P L L R P M E G G L P A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34322 672 74805 L454 W S K P L T L L H A F T C P A
Sea Urchin Strong. purpuratus XP_780438 570 63240 D366 I D K E G T E D V I S G I I N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJI2 643 70138 A443 Q D D V S L Q A C G V A Y F F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.9 98.8 87.6 N.A. 94.3 59.6 N.A. 81.7 36.5 N.A. 35.8 N.A. 33.4 N.A. 22.9 46.4
Protein Similarity: 100 92 99.5 91.5 N.A. 97.1 73.4 N.A. 88.5 52 N.A. 53.2 N.A. 52.4 N.A. 42.7 62.6
P-Site Identity: 100 93.3 86.6 86.6 N.A. 73.3 20 N.A. 60 13.3 N.A. 0 N.A. 0 N.A. 0 13.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 40 N.A. 73.3 26.6 N.A. 0 N.A. 6.6 N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 16 0 0 0 0 0 16 0 8 0 54 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % C
% Asp: 0 39 16 0 8 0 8 16 0 0 8 0 0 0 39 % D
% Glu: 16 0 0 8 0 0 8 0 0 8 47 0 0 0 16 % E
% Phe: 8 0 47 0 0 0 54 0 0 0 8 0 0 8 8 % F
% Gly: 0 8 0 0 8 0 0 0 0 8 8 24 8 39 0 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 8 0 8 8 0 % I
% Lys: 0 0 16 0 0 0 0 0 8 0 0 0 16 0 8 % K
% Leu: 0 0 0 47 24 16 16 16 0 0 0 8 8 16 8 % L
% Met: 0 0 8 0 0 0 0 0 39 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 8 31 0 54 0 8 8 62 0 0 8 16 0 % P
% Gln: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 0 0 8 0 0 8 0 0 31 8 0 % R
% Ser: 0 16 0 0 54 8 0 47 0 0 16 0 0 0 0 % S
% Thr: 8 8 0 0 8 16 0 0 0 0 0 16 0 0 0 % T
% Val: 8 8 0 8 0 0 0 0 24 0 8 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _