KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLCN
All Species:
0.61
Human Site:
S316
Identified Species:
1.11
UniProt:
Q8NFG4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFG4
NP_653207.1
579
64473
S316
K
A
P
V
L
P
E
S
T
E
G
R
E
L
T
Chimpanzee
Pan troglodytes
XP_001160873
582
64513
G316
K
A
P
V
L
P
E
G
T
E
G
R
E
L
T
Rhesus Macaque
Macaca mulatta
XP_001088928
579
64261
G316
K
A
P
V
L
T
E
G
V
E
G
R
E
L
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS3
579
64309
G316
K
A
P
V
T
P
E
G
A
E
G
R
E
L
T
Rat
Rattus norvegicus
Q76JQ2
579
64103
G316
K
A
P
A
T
A
E
G
A
E
G
R
E
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510766
579
64602
V316
K
A
P
T
L
P
E
V
P
E
G
R
E
L
S
Chicken
Gallus gallus
XP_414807
579
64831
E316
S
S
Q
P
D
V
A
E
G
Q
E
L
S
K
C
Frog
Xenopus laevis
NP_001121308
579
64849
M316
L
H
P
Q
P
E
P
M
E
G
R
E
L
S
K
Zebra Danio
Brachydanio rerio
NP_001035463
558
62158
S296
D
G
A
E
G
G
G
S
N
P
Q
S
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648090
460
51900
H212
E
H
I
F
A
Q
L
H
S
H
F
S
W
L
L
Honey Bee
Apis mellifera
XP_624515
471
53289
N223
F
I
E
I
F
P
M
N
L
L
D
D
E
L
N
Nematode Worm
Caenorhab. elegans
NP_001022107
635
71518
E384
Q
D
M
M
V
L
L
E
L
E
E
S
Q
I
V
Sea Urchin
Strong. purpuratus
XP_790040
519
58408
I270
L
K
A
G
G
N
R
I
T
E
K
V
L
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
98.7
N.A.
N.A.
92.5
92.7
N.A.
92.2
87.9
82.2
62.1
N.A.
25.7
28.6
22.2
41.9
Protein Similarity:
100
95.6
98.9
N.A.
N.A.
94.8
94.8
N.A.
96.1
93.4
89.2
73.4
N.A.
43.1
46.9
39.2
59
P-Site Identity:
100
93.3
80
N.A.
N.A.
80
60
N.A.
73.3
0
6.6
6.6
N.A.
6.6
20
6.6
13.3
P-Site Similarity:
100
93.3
80
N.A.
N.A.
80
60
N.A.
80
13.3
6.6
13.3
N.A.
20
33.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
16
8
8
8
8
0
16
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
0
0
8
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
8
0
8
8
0
8
47
16
8
62
16
8
54
8
0
% E
% Phe:
8
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
8
16
8
8
31
8
8
47
0
0
0
8
% G
% His:
0
16
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
47
8
0
0
0
0
0
0
0
0
8
0
0
8
8
% K
% Leu:
16
0
0
0
31
8
16
0
16
8
0
8
16
62
8
% L
% Met:
0
0
8
8
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
8
% N
% Pro:
0
0
54
8
8
39
8
0
8
8
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
8
0
0
0
8
8
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
8
47
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
16
8
0
0
24
16
8
16
% S
% Thr:
0
0
0
8
16
8
0
0
24
0
0
0
0
0
31
% T
% Val:
0
0
0
31
8
8
0
8
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _