Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLCN All Species: 9.39
Human Site: S331 Identified Species: 17.22
UniProt: Q8NFG4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFG4 NP_653207.1 579 64473 S331 Q G P A E S S S L S G C G S W
Chimpanzee Pan troglodytes XP_001160873 582 64513 S331 Q G P A E S S S L S G C G S W
Rhesus Macaque Macaca mulatta XP_001088928 579 64261 S331 Q G T A E S S S L S G C G S W
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8QZS3 579 64309 F331 S C P T E S S F L S A C G S W
Rat Rattus norvegicus Q76JQ2 579 64103 F331 S C P T E S S F L S A C G S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510766 579 64602 L331 K C P N E S S L L S D C G A W
Chicken Gallus gallus XP_414807 579 64831 P331 S P E T S L M P D C N R W N V
Frog Xenopus laevis NP_001121308 579 64849 L331 C P T E S S V L S D C S W N M
Zebra Danio Brachydanio rerio NP_001035463 558 62158 F311 E S V Q A K D F Q F D D R R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648090 460 51900 T227 L A G S R F L T E H V T F G N
Honey Bee Apis mellifera XP_624515 471 53289 E238 Y N L E H Q I E T E D G F T L
Nematode Worm Caenorhab. elegans NP_001022107 635 71518 N399 E L E L R H P N Q H L V S M A
Sea Urchin Strong. purpuratus XP_790040 519 58408 D285 P P L E E A V D L D D E E A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 98.7 N.A. N.A. 92.5 92.7 N.A. 92.2 87.9 82.2 62.1 N.A. 25.7 28.6 22.2 41.9
Protein Similarity: 100 95.6 98.9 N.A. N.A. 94.8 94.8 N.A. 96.1 93.4 89.2 73.4 N.A. 43.1 46.9 39.2 59
P-Site Identity: 100 100 93.3 N.A. N.A. 66.6 66.6 N.A. 60 0 6.6 0 N.A. 0 0 0 13.3
P-Site Similarity: 100 100 93.3 N.A. N.A. 66.6 66.6 N.A. 73.3 6.6 13.3 6.6 N.A. 13.3 6.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 24 8 8 0 0 0 0 16 0 0 16 8 % A
% Cys: 8 24 0 0 0 0 0 0 0 8 8 47 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 8 16 31 8 0 0 0 % D
% Glu: 16 0 16 24 54 0 0 8 8 8 0 8 8 0 0 % E
% Phe: 0 0 0 0 0 8 0 24 0 8 0 0 16 0 0 % F
% Gly: 0 24 8 0 0 0 0 0 0 0 24 8 47 8 0 % G
% His: 0 0 0 0 8 8 0 0 0 16 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % K
% Leu: 8 8 16 8 0 8 8 16 54 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % M
% Asn: 0 8 0 8 0 0 0 8 0 0 8 0 0 16 8 % N
% Pro: 8 24 39 0 0 0 8 8 0 0 0 0 0 0 0 % P
% Gln: 24 0 0 8 0 8 0 0 16 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 16 0 0 0 0 0 0 8 8 8 0 % R
% Ser: 24 8 0 8 16 54 47 24 8 47 0 8 8 39 0 % S
% Thr: 0 0 16 24 0 0 0 8 8 0 0 8 0 8 0 % T
% Val: 0 0 8 0 0 0 16 0 0 0 8 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 47 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _