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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLCN
All Species:
15.15
Human Site:
T323
Identified Species:
27.78
UniProt:
Q8NFG4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFG4
NP_653207.1
579
64473
T323
S
T
E
G
R
E
L
T
Q
G
P
A
E
S
S
Chimpanzee
Pan troglodytes
XP_001160873
582
64513
T323
G
T
E
G
R
E
L
T
Q
G
P
A
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001088928
579
64261
T323
G
V
E
G
R
E
L
T
Q
G
T
A
E
S
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS3
579
64309
T323
G
A
E
G
R
E
L
T
S
C
P
T
E
S
S
Rat
Rattus norvegicus
Q76JQ2
579
64103
A323
G
A
E
G
R
E
L
A
S
C
P
T
E
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510766
579
64602
S323
V
P
E
G
R
E
L
S
K
C
P
N
E
S
S
Chicken
Gallus gallus
XP_414807
579
64831
C323
E
G
Q
E
L
S
K
C
S
P
E
T
S
L
M
Frog
Xenopus laevis
NP_001121308
579
64849
K323
M
E
G
R
E
L
S
K
C
P
T
E
S
S
V
Zebra Danio
Brachydanio rerio
NP_001035463
558
62158
S303
S
N
P
Q
S
S
Q
S
E
S
V
Q
A
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648090
460
51900
L219
H
S
H
F
S
W
L
L
L
A
G
S
R
F
L
Honey Bee
Apis mellifera
XP_624515
471
53289
N230
N
L
L
D
D
E
L
N
Y
N
L
E
H
Q
I
Nematode Worm
Caenorhab. elegans
NP_001022107
635
71518
V391
E
L
E
E
S
Q
I
V
E
L
E
L
R
H
P
Sea Urchin
Strong. purpuratus
XP_790040
519
58408
G277
I
T
E
K
V
L
E
G
P
P
L
E
E
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
98.7
N.A.
N.A.
92.5
92.7
N.A.
92.2
87.9
82.2
62.1
N.A.
25.7
28.6
22.2
41.9
Protein Similarity:
100
95.6
98.9
N.A.
N.A.
94.8
94.8
N.A.
96.1
93.4
89.2
73.4
N.A.
43.1
46.9
39.2
59
P-Site Identity:
100
93.3
80
N.A.
N.A.
66.6
60
N.A.
60
0
6.6
6.6
N.A.
6.6
13.3
6.6
20
P-Site Similarity:
100
93.3
80
N.A.
N.A.
66.6
60
N.A.
73.3
6.6
6.6
20
N.A.
20
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
8
0
8
0
24
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
24
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
16
8
62
16
8
54
8
0
16
0
16
24
54
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
31
8
8
47
0
0
0
8
0
24
8
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
8
8
8
0
0
0
0
8
0
% K
% Leu:
0
16
8
0
8
16
62
8
8
8
16
8
0
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
0
8
0
8
0
8
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
8
24
39
0
0
0
8
% P
% Gln:
0
0
8
8
0
8
8
0
24
0
0
8
0
8
0
% Q
% Arg:
0
0
0
8
47
0
0
0
0
0
0
0
16
0
0
% R
% Ser:
16
8
0
0
24
16
8
16
24
8
0
8
16
54
47
% S
% Thr:
0
24
0
0
0
0
0
31
0
0
16
24
0
0
0
% T
% Val:
8
8
0
0
8
0
0
8
0
0
8
0
0
0
16
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _