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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP43 All Species: 36.67
Human Site: S255 Identified Species: 67.22
UniProt: Q8NFH3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH3 NP_942590.1 380 42151 S255 R Q G T M P V S L L K A H E A
Chimpanzee Pan troglodytes XP_527530 441 48425 S316 R Q G T M P V S L L K A H E A
Rhesus Macaque Macaca mulatta XP_001086760 377 42017 S252 R Q G T M P V S L L K A R E A
Dog Lupus familis XP_541148 380 41937 S255 R Q G T M P V S L L K A H E A
Cat Felis silvestris
Mouse Mus musculus P59235 380 41996 S255 R Q G T M P V S L L K A H E A
Rat Rattus norvegicus NP_001121663 352 38888 S229 R Q G T M P V S L L K A H E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506181 401 44017 S276 R Q G S M P V S L L K A H E A
Chicken Gallus gallus XP_419667 374 41676 M251 W D I R Q G T M P V S L L N A
Frog Xenopus laevis NP_001090382 375 41678 S252 R H G K M P M S L L N A H E A
Zebra Danio Brachydanio rerio NP_998057 372 40732 S249 R Q G N T P F S L T E A H S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650716 358 40130 L235 H P M Q Q H I L L C G S E E G
Honey Bee Apis mellifera XP_624212 346 39086 V223 H P T Q R H I V V A G G G D G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784173 502 55439 T368 R K E Q L P V T L F D V H Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 89.2 95 N.A. 93.1 85.7 N.A. 72.5 75.2 68.9 60.7 N.A. 28.1 34.7 N.A. 36.2
Protein Similarity: 100 86.1 91.5 98.6 N.A. 97.1 90.2 N.A. 79 85 81 75.5 N.A. 50.5 52.1 N.A. 52.7
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 6.6 73.3 60 N.A. 13.3 0 N.A. 33.3
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 100 13.3 80 66.6 N.A. 26.6 20 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 70 0 0 77 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 8 0 8 70 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 70 0 0 8 0 0 0 0 16 8 8 0 16 % G
% His: 16 8 0 0 0 16 0 0 0 0 0 0 70 0 0 % H
% Ile: 0 0 8 0 0 0 16 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 0 0 0 0 0 0 54 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 8 85 62 0 8 8 0 0 % L
% Met: 0 0 8 0 62 0 8 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 8 0 0 8 0 % N
% Pro: 0 16 0 0 0 77 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 62 0 24 16 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 77 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 0 0 0 8 0 0 0 70 0 0 8 8 0 8 8 % S
% Thr: 0 0 8 47 8 0 8 8 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 62 8 8 8 0 8 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _