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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP43 All Species: 21.52
Human Site: S292 Identified Species: 39.44
UniProt: Q8NFH3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH3 NP_942590.1 380 42151 S292 S L W H W D A S T D V P E K S
Chimpanzee Pan troglodytes XP_527530 441 48425 S353 S L W H W D A S T D V P E K S
Rhesus Macaque Macaca mulatta XP_001086760 377 42017 S289 A L W H W D A S T D V P E K L
Dog Lupus familis XP_541148 380 41937 S292 S L W H W D A S T D V P E K S
Cat Felis silvestris
Mouse Mus musculus P59235 380 41996 S292 S L W H W D A S T N A P E K S
Rat Rattus norvegicus NP_001121663 352 38888 D264 D G S L W H W D A S T N A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506181 401 44017 S313 S L W H W D A S S D L S E K P
Chicken Gallus gallus XP_419667 374 41676 W286 C S E D G S L W H W D T S T D
Frog Xenopus laevis NP_001090382 375 41678 D287 D G S L W H W D A S A D S E K
Zebra Danio Brachydanio rerio NP_998057 372 40732 E284 D G S L L H W E S T S G S D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650716 358 40130 F271 S P I N E I G F H Q K D P S K
Honey Bee Apis mellifera XP_624212 346 39086 L258 A K A V S E I L F H P D R P E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784173 502 55439 G412 T K G Q S S T G S A F R N M N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 89.2 95 N.A. 93.1 85.7 N.A. 72.5 75.2 68.9 60.7 N.A. 28.1 34.7 N.A. 36.2
Protein Similarity: 100 86.1 91.5 98.6 N.A. 97.1 90.2 N.A. 79 85 81 75.5 N.A. 50.5 52.1 N.A. 52.7
P-Site Identity: 100 100 86.6 100 N.A. 86.6 6.6 N.A. 73.3 0 6.6 0 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 6.6 N.A. 86.6 0 13.3 6.6 N.A. 13.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 0 0 0 47 0 16 8 16 0 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 24 0 0 8 0 47 0 16 0 39 8 24 0 8 8 % D
% Glu: 0 0 8 0 8 8 0 8 0 0 0 0 47 8 16 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 8 0 0 0 0 % F
% Gly: 0 24 8 0 8 0 8 8 0 0 0 8 0 0 0 % G
% His: 0 0 0 47 0 24 0 0 16 8 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 0 0 0 0 0 0 0 0 8 0 0 47 16 % K
% Leu: 0 47 0 24 8 0 8 8 0 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 8 0 8 8 0 8 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 8 39 8 16 8 % P
% Gln: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % R
% Ser: 47 8 24 0 16 16 0 47 24 16 8 8 24 8 31 % S
% Thr: 8 0 0 0 0 0 8 0 39 8 8 8 0 8 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 31 0 0 0 8 % V
% Trp: 0 0 47 0 62 0 24 8 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _