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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP43
All Species:
27.27
Human Site:
T251
Identified Species:
50
UniProt:
Q8NFH3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFH3
NP_942590.1
380
42151
T251
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Chimpanzee
Pan troglodytes
XP_527530
441
48425
T312
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Rhesus Macaque
Macaca mulatta
XP_001086760
377
42017
T248
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Dog
Lupus familis
XP_541148
380
41937
T251
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P59235
380
41996
T251
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Rat
Rattus norvegicus
NP_001121663
352
38888
T225
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506181
401
44017
S272
I
W
D
V
R
Q
G
S
M
P
V
S
L
L
K
Chicken
Gallus gallus
XP_419667
374
41676
R247
M
L
S
I
W
D
I
R
Q
G
T
M
P
V
S
Frog
Xenopus laevis
NP_001090382
375
41678
K248
I
W
D
V
R
H
G
K
M
P
M
S
L
L
N
Zebra Danio
Brachydanio rerio
NP_998057
372
40732
N245
I
W
D
V
R
Q
G
N
T
P
F
S
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650716
358
40130
Q231
S
L
A
K
H
P
M
Q
Q
H
I
L
L
C
G
Honey Bee
Apis mellifera
XP_624212
346
39086
Q219
S
I
A
H
H
P
T
Q
R
H
I
V
V
A
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784173
502
55439
Q364
I
W
D
M
R
K
E
Q
L
P
V
T
L
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
89.2
95
N.A.
93.1
85.7
N.A.
72.5
75.2
68.9
60.7
N.A.
28.1
34.7
N.A.
36.2
Protein Similarity:
100
86.1
91.5
98.6
N.A.
97.1
90.2
N.A.
79
85
81
75.5
N.A.
50.5
52.1
N.A.
52.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
0
73.3
66.6
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
80
73.3
N.A.
13.3
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
77
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
70
0
0
8
0
0
0
0
16
% G
% His:
0
0
0
8
16
8
0
0
0
16
0
0
0
0
0
% H
% Ile:
77
8
0
8
0
0
8
0
0
0
16
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
54
% K
% Leu:
0
16
0
0
0
0
0
0
8
0
0
8
85
62
0
% L
% Met:
8
0
0
8
0
0
8
0
62
0
8
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
16
0
0
0
77
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
62
0
24
16
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
77
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
16
0
8
0
0
0
0
8
0
0
0
70
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
47
8
0
8
8
0
8
0
% T
% Val:
0
0
0
70
0
0
0
0
0
0
62
8
8
8
0
% V
% Trp:
0
77
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _