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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP43 All Species: 27.27
Human Site: T251 Identified Species: 50
UniProt: Q8NFH3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH3 NP_942590.1 380 42151 T251 I W D V R Q G T M P V S L L K
Chimpanzee Pan troglodytes XP_527530 441 48425 T312 I W D V R Q G T M P V S L L K
Rhesus Macaque Macaca mulatta XP_001086760 377 42017 T248 I W D V R Q G T M P V S L L K
Dog Lupus familis XP_541148 380 41937 T251 I W D V R Q G T M P V S L L K
Cat Felis silvestris
Mouse Mus musculus P59235 380 41996 T251 I W D V R Q G T M P V S L L K
Rat Rattus norvegicus NP_001121663 352 38888 T225 I W D V R Q G T M P V S L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506181 401 44017 S272 I W D V R Q G S M P V S L L K
Chicken Gallus gallus XP_419667 374 41676 R247 M L S I W D I R Q G T M P V S
Frog Xenopus laevis NP_001090382 375 41678 K248 I W D V R H G K M P M S L L N
Zebra Danio Brachydanio rerio NP_998057 372 40732 N245 I W D V R Q G N T P F S L T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650716 358 40130 Q231 S L A K H P M Q Q H I L L C G
Honey Bee Apis mellifera XP_624212 346 39086 Q219 S I A H H P T Q R H I V V A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784173 502 55439 Q364 I W D M R K E Q L P V T L F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 89.2 95 N.A. 93.1 85.7 N.A. 72.5 75.2 68.9 60.7 N.A. 28.1 34.7 N.A. 36.2
Protein Similarity: 100 86.1 91.5 98.6 N.A. 97.1 90.2 N.A. 79 85 81 75.5 N.A. 50.5 52.1 N.A. 52.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 0 73.3 66.6 N.A. 6.6 0 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 80 73.3 N.A. 13.3 13.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 77 0 0 8 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 70 0 0 8 0 0 0 0 16 % G
% His: 0 0 0 8 16 8 0 0 0 16 0 0 0 0 0 % H
% Ile: 77 8 0 8 0 0 8 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 8 0 8 0 8 0 0 0 0 0 0 54 % K
% Leu: 0 16 0 0 0 0 0 0 8 0 0 8 85 62 0 % L
% Met: 8 0 0 8 0 0 8 0 62 0 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 16 0 0 0 77 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 62 0 24 16 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 77 0 0 8 8 0 0 0 0 0 0 % R
% Ser: 16 0 8 0 0 0 0 8 0 0 0 70 0 0 8 % S
% Thr: 0 0 0 0 0 0 8 47 8 0 8 8 0 8 0 % T
% Val: 0 0 0 70 0 0 0 0 0 0 62 8 8 8 0 % V
% Trp: 0 77 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _