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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP35 All Species: 27.88
Human Site: S261 Identified Species: 47.18
UniProt: Q8NFH5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH5 NP_612142.2 326 34774 S261 R C A L S S P S L A F T P P I
Chimpanzee Pan troglodytes XP_001160265 337 36129 S272 R C A L S S P S L A F T P P I
Rhesus Macaque Macaca mulatta XP_001102848 326 34769 S261 R C A L S S P S L A F T P P I
Dog Lupus familis XP_535992 406 43346 S341 R C A L S S P S L A F T P P I
Cat Felis silvestris
Mouse Mus musculus Q8R4R6 325 34767 S260 R G V L S S P S L A F T T P I
Rat Rattus norvegicus Q68FY1 325 34783 S260 R G V L S S P S L A F T P P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516155 235 24557 P171 W V T V F G F P Q A S A S Y I
Chicken Gallus gallus XP_421854 325 34473 P260 R S S A S S M P S V F T P P S
Frog Xenopus laevis NP_001085157 318 33973 S252 K V T T P S V S S V F T P P V
Zebra Danio Brachydanio rerio Q6P6X9 308 32866 S243 S L D K G S T S S S V F T P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573314 331 35081 S265 V S R C T D R S V I D K E N I
Honey Bee Apis mellifera XP_396287 584 64120 P519 S I M I G V I P C T D E G R L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200424 554 60750 T279 S D S Y G V N T T G I M D T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03790 475 52600 T338 N G I I M N G T L I G C V S Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 99.6 78 N.A. 92.9 94.4 N.A. 63.1 83.4 73.3 71.4 N.A. 27.1 22.6 N.A. 24.3
Protein Similarity: 100 95.8 100 79.3 N.A. 96 97.2 N.A. 65.9 91.4 84 82.2 N.A. 45 32.5 N.A. 36.4
P-Site Identity: 100 100 100 100 N.A. 80 86.6 N.A. 13.3 46.6 40 20 N.A. 13.3 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 80 86.6 N.A. 20 53.3 53.3 26.6 N.A. 26.6 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 29 8 0 0 0 0 0 50 0 8 0 0 0 % A
% Cys: 0 29 0 8 0 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 0 8 8 0 0 8 0 0 0 0 15 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 0 58 8 0 0 0 % F
% Gly: 0 22 0 0 22 8 8 0 0 8 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 15 0 0 8 0 0 15 8 0 0 0 58 % I
% Lys: 8 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 8 0 43 0 0 0 0 50 0 0 0 0 0 8 % L
% Met: 0 0 8 0 8 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 8 0 43 22 0 0 0 0 50 65 15 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 50 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % R
% Ser: 22 15 15 0 50 65 0 65 22 8 8 0 8 8 8 % S
% Thr: 0 0 15 8 8 0 8 15 8 8 0 58 15 8 0 % T
% Val: 8 15 15 8 0 15 8 0 8 15 8 0 8 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _