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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP35
All Species:
30.61
Human Site:
T280
Identified Species:
51.79
UniProt:
Q8NFH5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFH5
NP_612142.2
326
34774
T280
T
P
T
Q
P
G
S
T
P
R
I
S
T
M
R
Chimpanzee
Pan troglodytes
XP_001160265
337
36129
T291
T
P
T
Q
P
G
S
T
P
R
I
S
T
M
R
Rhesus Macaque
Macaca mulatta
XP_001102848
326
34769
T280
T
P
T
Q
P
G
S
T
P
R
I
S
T
M
R
Dog
Lupus familis
XP_535992
406
43346
T360
T
P
T
Q
P
G
S
T
P
R
I
S
T
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4R6
325
34767
T279
T
P
T
Q
S
G
S
T
P
R
V
S
T
M
R
Rat
Rattus norvegicus
Q68FY1
325
34783
T279
T
P
T
Q
P
G
S
T
P
R
V
S
T
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516155
235
24557
K190
A
Q
Y
G
N
I
L
K
H
V
M
S
N
T
G
Chicken
Gallus gallus
XP_421854
325
34473
T279
T
P
V
Q
P
A
N
T
T
K
I
S
T
M
R
Frog
Xenopus laevis
NP_001085157
318
33973
T271
T
P
T
Q
S
A
G
T
P
R
A
A
S
M
R
Zebra Danio
Brachydanio rerio
Q6P6X9
308
32866
S262
C
T
P
S
H
P
L
S
T
P
R
S
V
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573314
331
35081
P284
N
A
E
I
G
D
P
P
T
S
P
S
A
I
R
Honey Bee
Apis mellifera
XP_396287
584
64120
P538
E
Y
S
T
P
R
T
P
I
R
I
Q
S
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200424
554
60750
A298
K
R
L
V
S
Q
N
A
E
P
E
A
V
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03790
475
52600
K357
L
K
Q
L
A
S
L
K
K
S
E
E
I
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
99.6
78
N.A.
92.9
94.4
N.A.
63.1
83.4
73.3
71.4
N.A.
27.1
22.6
N.A.
24.3
Protein Similarity:
100
95.8
100
79.3
N.A.
96
97.2
N.A.
65.9
91.4
84
82.2
N.A.
45
32.5
N.A.
36.4
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
66.6
60
20
N.A.
13.3
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
80
73.3
26.6
N.A.
20
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
15
0
8
0
0
8
15
8
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
8
0
15
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
43
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
8
0
43
0
8
15
0
% I
% Lys:
8
8
0
0
0
0
0
15
8
8
0
0
0
0
0
% K
% Leu:
8
0
8
8
0
0
22
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
65
0
% M
% Asn:
8
0
0
0
8
0
15
0
0
0
0
0
8
0
8
% N
% Pro:
0
58
8
0
50
8
8
15
50
15
8
0
0
0
0
% P
% Gln:
0
8
8
58
0
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
58
8
0
0
8
86
% R
% Ser:
0
0
8
8
22
8
43
8
0
15
0
72
15
0
0
% S
% Thr:
58
8
50
8
0
0
8
58
22
0
0
0
50
8
0
% T
% Val:
0
0
8
8
0
0
0
0
0
8
15
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _