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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENGASE All Species: 15.45
Human Site: S119 Identified Species: 28.33
UniProt: Q8NFI3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFI3 NP_001036038.1 743 83987 S119 A C R Q P P L S S Q R P R T L
Chimpanzee Pan troglodytes XP_001159278 743 84023 S119 A C R Q P P L S S Q R P R T L
Rhesus Macaque Macaca mulatta XP_001107425 771 86711 S147 A C R Q P P L S S Q R P R T L
Dog Lupus familis XP_540466 711 79811 Y99 C H D M M G G Y L D D K F I Q
Cat Felis silvestris
Mouse Mus musculus Q8BX80 734 82927 S111 V C R R P P L S S P R P R T L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518787 252 28417
Chicken Gallus gallus P0C7A1 728 80871 H117 A Q R Q P P L H S R R P R T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1L251 713 80236 S98 S R Y P P L E S C P R R T L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573215 655 75729 D102 R V R S R N I D W R E Y V L P
Honey Bee Apis mellifera XP_001121069 578 67421 W27 N V D N L K P W P D I K K L R
Nematode Worm Caenorhab. elegans NP_001021238 433 50225
Sea Urchin Strong. purpuratus XP_794341 764 85326 T118 L M L G T V I T E W Q D G K K
Poplar Tree Populus trichocarpa XP_002315137 698 78027 V107 W Y L I D V F V Y F S H N L V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 89.8 77.3 N.A. 78.7 N.A. N.A. 22 53.2 N.A. 47.6 N.A. 28.5 28.3 25.4 25.5
Protein Similarity: 100 99.7 92.6 82.9 N.A. 85.3 N.A. N.A. 26.1 65.8 N.A. 63.5 N.A. 43.6 43.2 37 42.1
P-Site Identity: 100 100 100 0 N.A. 80 N.A. N.A. 0 80 N.A. 20 N.A. 6.6 0 0 0
P-Site Similarity: 100 100 100 0 N.A. 86.6 N.A. N.A. 0 86.6 N.A. 33.3 N.A. 20 6.6 0 20
Percent
Protein Identity: 27.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 46.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 8 31 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 8 0 0 8 0 16 8 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 8 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 8 0 8 8 0 0 0 0 0 8 0 0 % G
% His: 0 8 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 8 0 0 16 0 0 0 8 0 0 8 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 16 8 8 8 % K
% Leu: 8 0 16 0 8 8 39 0 8 0 0 0 0 31 39 % L
% Met: 0 8 0 8 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 8 47 39 8 0 8 16 0 39 0 0 8 % P
% Gln: 0 8 0 31 0 0 0 0 0 24 8 0 0 0 8 % Q
% Arg: 8 8 47 8 8 0 0 0 0 16 47 8 39 0 8 % R
% Ser: 8 0 0 8 0 0 0 39 39 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 8 0 0 0 0 8 39 0 % T
% Val: 8 16 0 0 0 16 0 8 0 0 0 0 8 0 16 % V
% Trp: 8 0 0 0 0 0 0 8 8 8 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 8 8 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _