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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
4.85
Human Site:
S49
Identified Species:
8.89
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
S49
R
R
R
R
P
G
R
S
I
K
D
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
S49
R
R
R
R
P
G
R
S
I
R
D
G
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
R77
R
R
R
R
P
G
R
R
I
K
D
D
E
E
E
Dog
Lupus familis
XP_540466
711
79811
T44
R
Y
Y
D
K
D
T
T
K
P
V
S
F
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
Q45
G
R
R
I
N
E
D
Q
E
E
E
A
V
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
Chicken
Gallus gallus
P0C7A1
728
80871
F47
F
S
G
H
L
I
N
F
Q
P
A
A
E
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
F43
S
V
H
E
V
V
T
F
E
P
S
T
L
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
K44
E
E
V
V
P
V
K
K
K
R
T
E
E
G
G
Honey Bee
Apis mellifera
XP_001121069
578
67421
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
D55
P
M
T
L
V
C
H
D
M
K
G
G
Y
I
D
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
F48
S
R
A
Y
F
K
S
F
H
C
P
F
N
I
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
86.6
86.6
6.6
N.A.
13.3
N.A.
N.A.
0
6.6
N.A.
0
N.A.
20
0
0
6.6
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
26.6
N.A.
N.A.
0
6.6
N.A.
0
N.A.
33.3
0
0
20
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
0
0
8
0
8
8
8
0
0
24
8
0
0
8
% D
% Glu:
8
8
0
8
0
8
0
0
16
8
8
16
39
24
24
% E
% Phe:
8
0
0
0
8
0
0
24
0
0
0
8
8
8
8
% F
% Gly:
8
0
8
0
0
24
0
0
0
0
8
16
0
8
8
% G
% His:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
24
0
0
0
0
16
0
% I
% Lys:
0
0
0
0
8
8
8
8
16
24
0
0
0
0
0
% K
% Leu:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
8
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
31
0
0
0
0
24
8
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
31
39
31
24
0
0
24
8
0
16
0
0
0
0
8
% R
% Ser:
16
8
0
0
0
0
8
16
0
0
8
8
0
0
8
% S
% Thr:
0
0
8
0
0
0
16
8
0
0
8
8
0
0
0
% T
% Val:
0
8
8
8
16
16
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
8
0
0
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _