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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
15.15
Human Site:
S586
Identified Species:
27.78
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
S586
L
D
L
L
V
C
F
S
R
P
P
G
S
R
E
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
S586
L
D
L
L
V
C
F
S
R
P
P
G
S
R
E
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
S614
L
D
L
L
V
C
F
S
R
P
P
G
S
R
E
Dog
Lupus familis
XP_540466
711
79811
A549
R
D
L
F
V
S
F
A
R
P
P
G
S
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
S577
Q
D
L
L
V
S
F
S
R
P
P
G
S
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
D130
F
Y
H
W
Q
H
I
D
I
F
V
Y
F
S
H
Chicken
Gallus gallus
P0C7A1
728
80871
S582
R
D
L
S
L
L
V
S
R
Q
Q
A
S
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
V558
L
R
E
V
C
I
R
V
S
R
D
G
G
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
R533
T
M
F
D
L
L
V
R
V
T
P
L
R
R
N
Honey Bee
Apis mellifera
XP_001121069
578
67421
E456
R
L
F
L
V
H
I
E
F
Q
Q
D
I
E
A
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
I311
R
T
R
P
L
T
S
I
N
F
G
T
N
F
C
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
L609
A
K
I
T
E
I
G
L
L
C
F
S
A
A
P
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
I567
Y
H
A
V
L
G
H
I
T
M
N
T
S
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
100
100
73.3
N.A.
86.6
N.A.
N.A.
0
33.3
N.A.
20
N.A.
13.3
13.3
0
0
P-Site Similarity:
100
100
100
80
N.A.
86.6
N.A.
N.A.
0
46.6
N.A.
26.6
N.A.
20
13.3
13.3
13.3
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
8
24
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
47
0
8
0
0
0
8
0
0
8
8
0
8
0
% D
% Glu:
0
0
8
0
8
0
0
8
0
0
0
0
0
8
54
% E
% Phe:
8
0
16
8
0
0
39
0
8
16
8
0
8
8
0
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
8
47
8
0
0
% G
% His:
0
8
8
0
0
16
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
16
16
16
8
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
31
8
47
39
31
16
0
8
8
0
0
8
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
8
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
39
47
0
0
8
8
% P
% Gln:
8
0
0
0
8
0
0
0
0
16
16
0
0
0
8
% Q
% Arg:
31
8
8
0
0
0
8
8
47
8
0
0
8
47
0
% R
% Ser:
0
0
0
8
0
16
8
39
8
0
0
8
54
8
0
% S
% Thr:
8
8
0
8
0
8
0
0
8
8
0
16
0
0
0
% T
% Val:
0
0
0
16
47
0
16
8
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _