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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
24.55
Human Site:
S596
Identified Species:
45
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
S596
P
G
S
R
E
E
E
S
F
T
C
R
L
G
E
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
S596
P
G
S
R
E
E
E
S
F
T
C
R
L
G
E
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
S624
P
G
S
R
E
E
E
S
F
T
C
R
L
G
E
Dog
Lupus familis
XP_540466
711
79811
S559
P
G
S
R
E
E
E
S
F
V
C
R
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
S587
P
G
S
R
E
E
E
S
F
I
C
R
L
G
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
L140
V
Y
F
S
H
R
L
L
T
I
P
P
V
G
W
Chicken
Gallus gallus
P0C7A1
728
80871
S592
Q
A
S
P
Q
E
T
S
F
S
C
L
L
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
N568
D
G
G
D
E
D
I
N
F
N
C
R
I
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
D543
P
L
R
R
N
D
Q
D
L
H
L
F
C
G
D
Honey Bee
Apis mellifera
XP_001121069
578
67421
I466
Q
D
I
E
A
T
I
I
Y
E
E
M
I
S
S
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
M321
G
T
N
F
C
T
G
M
D
Q
N
W
H
Y
R
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
S619
F
S
A
A
P
V
E
S
Y
S
V
K
I
G
E
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
Y577
N
T
S
K
E
N
T
Y
F
P
P
S
S
S
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
6.6
53.3
N.A.
46.6
N.A.
20
0
0
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
13.3
66.6
N.A.
66.6
N.A.
40
13.3
6.6
60
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
54
0
8
0
0
% C
% Asp:
8
8
0
8
0
16
0
8
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
54
47
47
0
0
8
8
0
0
0
62
% E
% Phe:
8
0
8
8
0
0
0
0
62
0
0
8
0
0
0
% F
% Gly:
8
47
8
0
0
0
8
0
0
0
0
0
0
77
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
0
0
0
16
8
0
16
0
0
24
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
0
0
8
8
8
0
8
8
47
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
8
0
8
8
0
8
0
8
8
0
0
0
0
% N
% Pro:
47
0
0
8
8
0
0
0
0
8
16
8
0
0
0
% P
% Gln:
16
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
47
0
8
0
0
0
0
0
47
0
0
8
% R
% Ser:
0
8
54
8
0
0
0
54
0
16
0
8
8
16
8
% S
% Thr:
0
16
0
0
0
16
16
0
8
24
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
0
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
16
% W
% Tyr:
0
8
0
0
0
0
0
8
16
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _