KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
10
Human Site:
S673
Identified Species:
18.33
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
S673
W
G
G
M
S
D
D
S
P
G
R
E
L
P
R
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
S673
W
G
G
M
S
D
D
S
P
G
R
E
L
P
R
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
S701
W
G
G
T
S
D
D
S
P
G
R
E
L
P
R
Dog
Lupus familis
XP_540466
711
79811
A636
C
V
G
T
G
G
G
A
L
G
G
G
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
S664
W
K
R
T
G
S
S
S
S
V
A
E
S
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
L217
A
P
R
F
L
R
Y
L
T
E
E
L
H
R
Q
Chicken
Gallus gallus
P0C7A1
728
80871
P669
H
R
A
Q
P
A
Q
P
Q
L
L
G
L
A
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
P645
R
H
L
R
G
P
D
P
R
I
P
S
G
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
A620
P
S
E
S
S
T
D
A
K
L
G
F
V
Y
V
Honey Bee
Apis mellifera
XP_001121069
578
67421
G543
E
I
I
L
E
Q
K
G
H
P
N
Y
Q
C
H
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
G398
S
E
I
M
D
K
T
G
D
S
T
W
H
I
D
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
N696
S
G
I
E
R
D
P
N
Q
S
R
A
V
S
K
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
E654
Y
L
G
V
A
N
V
E
A
F
Y
V
S
E
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
100
93.3
13.3
N.A.
26.6
N.A.
N.A.
0
6.6
N.A.
13.3
N.A.
13.3
0
6.6
20
P-Site Similarity:
100
100
93.3
20
N.A.
26.6
N.A.
N.A.
6.6
6.6
N.A.
13.3
N.A.
26.6
6.6
6.6
40
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
16
8
0
8
8
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
31
39
0
8
0
0
0
0
0
8
% D
% Glu:
8
8
8
8
8
0
0
8
0
8
8
31
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
31
39
0
24
8
8
16
0
31
16
16
8
0
8
% G
% His:
8
8
0
0
0
0
0
0
8
0
0
0
16
0
16
% H
% Ile:
0
8
24
0
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% K
% Leu:
0
8
8
8
8
0
0
8
8
16
8
8
31
0
16
% L
% Met:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% N
% Pro:
8
8
0
0
8
8
8
16
24
8
8
0
8
39
0
% P
% Gln:
0
0
0
8
0
8
8
0
16
0
0
0
8
0
8
% Q
% Arg:
8
8
16
8
8
8
0
0
8
0
31
0
0
8
24
% R
% Ser:
16
8
0
8
31
8
8
31
8
16
0
8
16
16
0
% S
% Thr:
0
0
0
24
0
8
8
0
8
0
8
0
0
0
0
% T
% Val:
0
8
0
8
0
0
8
0
0
8
0
8
16
0
8
% V
% Trp:
31
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
8
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _